Electrogenerated chemiluminescence biosensing method for methyltransferase activity using tris (1, 10-phenanthroline) ruthenium-assembled graphene oxide
Z Yan, Y Li, J Zheng, M Zhou - Journal of Electroanalytical Chemistry, 2014 - Elsevier
A novel electrogenerated chemiluminescence (ECL) biosensing method for highly sensitive
detection of DNA methylation and assay of the methyltransferase (MTase) activity was …
detection of DNA methylation and assay of the methyltransferase (MTase) activity was …
Adaptation of the CHARM DNA methylation platform for the rat genome reveals novel brain region-specific differences
Comprehensive High-throughput Arrays for Relative Methylation (CHARM) was recently
developed as an experimental platform and analytic approach to assess DNA methylation …
developed as an experimental platform and analytic approach to assess DNA methylation …
[HTML][HTML] A Practical Approach for Targeting Structural Variants Genome-wide in Plasma Cell-free DNA
Interrogating plasma cell-free DNA (cfDNA) to detect cancer offers promise; however, no
current tests scan structural variants (SVs) throughout the genome. Here, we report a simple …
current tests scan structural variants (SVs) throughout the genome. Here, we report a simple …
[HTML][HTML] The molecular and cellular basis of variable craniofacial phenotypes and their genetic rescue in Twisted gastrulation mutant mice
CJ Billington Jr, B Ng, C Forsman, B Schmidt… - Developmental …, 2011 - Elsevier
The severity of numerous developmental abnormalities can vary widely despite shared
genetic causes. Mice deficient in Twisted gastrulation (Twsg1−/−) display such phenotypic …
genetic causes. Mice deficient in Twisted gastrulation (Twsg1−/−) display such phenotypic …
Paradox of sonic hedgehog (SHH) transcriptional regulation: Alternative transcription initiation overrides the effect of downstream promoter DNA methylation
A ten Haaf, L Franken, C Heymann, S von Serenyi… - Epigenetics, 2011 - Taylor & Francis
Recently, DNA methylation has been suggested as a potential mechanism involved in the
transcriptional regulation of SHH gene expression in cancer. However, detailed analyses on …
transcriptional regulation of SHH gene expression in cancer. However, detailed analyses on …
Comparison of different normalization assumptions for analyses of DNA methylation data from the cancer genome
Nowadays, some researchers normalized DNA methylation arrays data in order to remove
the technical artifacts introduced by experimental differences in sample preparation, array …
the technical artifacts introduced by experimental differences in sample preparation, array …
Gene-Specific DNA Methylation Profiles in Pediatric Medulloblastomas
Introduction Medulloblastoma is the most common pediatric central nervous tumor of high
malignancy that has been classified into both histological subtypes and molecular …
malignancy that has been classified into both histological subtypes and molecular …
A Practical Approach for Targeting Structural Variants Genome-wide in Plasma Cell-free DNA
MM Murata, F Igari, R Urbanowicz, L Mouakkad, S Kim… - bioRxiv, 2023 - biorxiv.org
Interrogating plasma cell-free DNA (cfDNA) to detect cancer offers promise; however, no
current tests scan structural variants (SVs) throughout the genome. Here, we report a simple …
current tests scan structural variants (SVs) throughout the genome. Here, we report a simple …
[HTML][HTML] Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy
F Nitzki, EJ Tolosa, N Cuvelier, A Frommhold… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Mice with heterozygous loss of the tumor suppressor Patched1 (Ptch) develop
rhabdomyosarcoma (RMS)-like tumors. However, Ptch transcripts are consistently …
rhabdomyosarcoma (RMS)-like tumors. However, Ptch transcripts are consistently …
DAMD to epigenetic silence
For many decades, cancer research focused on genetic changes that led to tumorigenesis.
However, it is now established that epigenetics also plays an important role in cancer …
However, it is now established that epigenetics also plays an important role in cancer …