Heart failure after myocardial infarction: incidence and predictors

D Jenča, V Melenovský, J Stehlik, V Staněk… - ESC heart …, 2021 - Wiley Online Library
Aims The aim of the present paper was to provide an up‐to‐date view on epidemiology and
risk factors of heart failure (HF) development after myocardial infarction. Methods and results …

Matrix metalloproteinases in myocardial infarction and heart failure

KY DeLeon-Pennell, CA Meschiari, M Jung… - Progress in molecular …, 2017 - Elsevier
Cardiovascular disease is the leading cause of death, accounting for 600,000 deaths each
year in the United States. In addition, heart failure accounts for 37% of health care spending …

Long noncoding RNAs in patients with acute myocardial infarction

M Vausort, DR Wagner, Y Devaux - Circulation research, 2014 - Am Heart Assoc
Rationale: Long noncoding RNAs (lncRNAs) constitute a novel class of noncoding RNAs
that regulate gene expression. Although recent data suggest that lncRNAs may be …

Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function

FG Spinale - Physiological reviews, 2007 - journals.physiology.org
It is now becoming apparent that dynamic changes occur within the interstitium that directly
contribute to adverse myocardial remodeling following myocardial infarction (MI), with …

[HTML][HTML] Matrix metalloproteinase (MMP)-9: a proximal biomarker for cardiac remodeling and a distal biomarker for inflammation

GV Halade, YF Jin, ML Lindsey - Pharmacology & therapeutics, 2013 - Elsevier
Adverse cardiac remodeling following myocardial infarction (MI) remains a significant cause
of congestive heart failure. Additional and novel strategies that improve our ability to predict …

Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome

FS Apple, AHB Wu, J Mair, J Ravkilde… - Clinical …, 2005 - academic.oup.com
Background: Evaluation of patients who present to the hospital with a complaint of chest
pain or other signs or symptoms suggestive of acute coronary syndrome (ACS) is time …

Effect of neprilysin inhibition on left ventricular remodeling in patients with asymptomatic left ventricular systolic dysfunction late after myocardial infarction

KF Docherty, RT Campbell, KJM Brooksbank… - Circulation, 2021 - Am Heart Assoc
Background: Patients with left ventricular (LV) systolic dysfunction after myocardial infarction
are at a high risk of developing heart failure. The addition of neprilysin inhibition to renin …

Matrix metalloproteinase 2 as a pharmacological target in heart failure

PR Gonçalves, LD Nascimento, RF Gerlach… - Pharmaceuticals, 2022 - mdpi.com
Heart failure (HF) is an acute or chronic clinical syndrome that results in a decrease in
cardiac output and an increase in intracardiac pressure at rest or upon exertion. The …

Matrix metalloproteinases in coronary artery disease and myocardial infarction

H Bräuninger, S Krüger, L Bacmeister… - Basic Research in …, 2023 - Springer
Cardiovascular diseases (CVDs) remain the leading cause of death worldwide. Most
cardiovascular deaths are caused by ischaemic heart diseases such as myocardial …

Myofibroblasts and the extracellular matrix network in post-myocardial infarction cardiac remodeling

Y Ma, LE de Castro Brás, H Toba, RP Iyer… - … -European Journal of …, 2014 - Springer
The cardiac extracellular matrix (ECM) fills the space between cells, supports tissue
organization, and transduces mechanical, chemical, and biological signals to regulate …