Emerging cellular and immunotherapies for systemic sclerosis: from mesenchymal stromal cells to CAR-T cells and vaccine-based approaches

A Lescoat, H Kato, J Varga - Current Opinion in Rheumatology, 2023 - journals.lww.com
Building on the classification of the clinical phenotype and prediction of clinical trajectory
based on individual patients' autoantigen and/or autoantibody profile, cellular therapies …

THE SIGNIFICANCE OF AUTOANTIBODIES IN THE PATHOGENESIS OF SYSTEMIC SCLEROSIS (LITERATURE REVIEW)

ZS Istamovich, AK Sadullayevich… - … OF BIOMEDICINE AND …, 2023 - tadqiqot.uz
Systemic sclerosis is a progressive chronic autoimmune rheumatic disease with high
morbidity and mortality. Systemic sclerosis a multi-organ disease that affects organs such as …

CD64 plays a key role in diabetic wound healing

X Zhang, L Yuan, Z Tan, H Wu, F Chen… - Frontiers in …, 2024 - frontiersin.org
Introduction Wound healing poses a clinical challenge in diabetes mellitus (DM) due to
compromised host immunity. CD64, an IgG-binding Fcgr1 receptor, acts as a pro …

Molecular mechanisms behind the role of plasmacytoid dendritic cells in systemic sclerosis

IS Silva, BH Ferreira, CR Almeida - Biology, 2023 - mdpi.com
Simple Summary Systemic Sclerosis (SSc) is a rare autoimmune disease characterized by
scarring of the tissues and organs. This scarring, or fibrosis, has a major impact on a …

Plasticity and crosstalk of mesenchymal stem cells and macrophages in immunomodulation in sepsis

X Tao, J Wang, B Liu, P Cheng, D Mu, H Du… - Frontiers in …, 2024 - frontiersin.org
Sepsis is a multisystem disease characterized by dysregulation of the host immune
response to infection. Immune response kinetics play a crucial role in the pathogenesis and …

Neutrophil-Driven M2-Like Macrophages Are Critical for Skin Fibrosis in a Systemic Sclerosis Model

P Gong, Y Ding, W Li, J Yang, X Su, R Tian… - Journal of Investigative …, 2024 - Elsevier
Systemic sclerosis (SSc) is a challenging autoimmune disease characterized by progressive
fibrosis affecting the skin and internal organs. Despite the known infiltration of macrophages …

Mesenchymal Stem Cells in Autoimmune Disease: A Systematic Review and Meta-Analysis of Pre-Clinical Studies

HN Swain, PD Boyce, BA Bromet, K Barozinksy… - Biochimie, 2024 - Elsevier
ABSTRACT Mesenchymal Stem Cells (MSCs) are of interest in the clinic because of their
immunomodulation capabilities, capacity to act upstream of inflammation, and ability to …

Значение аутоантел в патогенезе системной склеродермии

Тизимли склеродермия прогрессияланиб борувчи, оғир асоратлар ва ўлим даражаси
юқори бўлган сурункали аутоиммун ревматик касаллик ҳисобланади. Тизимли …

MODERN PATHOGENETIC MECHANISMS OF SYSTEMIC SCLERODERMIA

BA Nazarkulovich - World Bulletin of Public Health, 2023 - scholarexpress.net
Systemic scleroderma is a chronic and often progressive autoimmune inflammation of the
connective tissue, characterized by fibrosis of the skin and internal organs, widespread …

Modern Pathogenetic Mechanisms of Systemic Scleroderma

BA Nazarkulovich - Texas Journal of Medical Science, 2023 - zienjournals.com
Systemic scleroderma is a chronic and often progressive autoimmune inflammation of the
connective tissue, characterized by fibrosis of the skin and internal organs, widespread …