Is the efficacy of oxytocin for autism diminished at higher dosages or repeated doses?: potential mechanisms and candidate solutions
H Yamasue - Peptides, 2023 - Elsevier
No approved pharmacological intervention currently exists to address the core symptoms of
autism spectrum disorder, a prevalent neurodevelopmental condition. However, there is a …
autism spectrum disorder, a prevalent neurodevelopmental condition. However, there is a …
[HTML][HTML] The effects of oxytocin administration on social and routinized behaviors in autism: A preregistered systematic review and meta-analysis
K Audunsdottir, AM Sartorius, H Kang, B Glaser… - …, 2024 - Elsevier
Oxytocin administration has demonstrated considerable promise for providing individualized
support for autistic people. However, studies evaluating the effects of oxytocin administration …
support for autistic people. However, studies evaluating the effects of oxytocin administration …
Infrequent intranasal oxytocin followed by positive social interaction improves symptoms in autistic children: a pilot randomized clinical trial
Introduction: There are currently no approved drug interventions for social behavior
dysfunction in autism spectrum disorder (ASD). Previous trials investigating effects of daily …
dysfunction in autism spectrum disorder (ASD). Previous trials investigating effects of daily …
Effects of multiple-dose intranasal oxytocin administration on social responsiveness in children with autism: a randomized, placebo-controlled trial
Background Intranasal administration of oxytocin is increasingly explored as a new
approach to facilitate social development and reduce disability associated with a diagnosis …
approach to facilitate social development and reduce disability associated with a diagnosis …
Can repeated intranasal oxytocin administration affect reduced neural sensitivity towards expressive faces in autism? A randomized controlled trial
M Moerkerke, N Daniels… - Journal of Child …, 2023 - Wiley Online Library
Background Autism spectrum disorder (ASD) is a neurodevelopmental condition
characterized by difficulties in social communication and interaction. Crucial for efficient …
characterized by difficulties in social communication and interaction. Crucial for efficient …
Integrative analysis prioritised oxytocin-related biomarkers associated with the aetiology of autism spectrum disorder
T Wang, T Zhao, L Liu, H Teng, T Fan, Y Li, Y Wang… - …, 2022 - thelancet.com
Background Autism spectrum disorder (ASD) is a neurodevelopmental disorder with high
phenotypic and genetic heterogeneity. The common variants of specific oxytocin-related …
phenotypic and genetic heterogeneity. The common variants of specific oxytocin-related …
Impact of magnesium on oxytocin receptor function
Simple Summary What is already known: Mg2+ levels modulate the affinity of oxytocin
receptors for oxytocin in vitro, low serum Mg2+ is correlated with migraine headache onset …
receptors for oxytocin in vitro, low serum Mg2+ is correlated with migraine headache onset …
Oro-mucosal administration of oxytocin using medicated lollipops alters social attention, similar to intranasal and lingual routes: Implications for therapeutic use
A key functional effect of intranasal administration of the neuropeptide oxytocin is on top-
down control of social attention. However, an oro-mucosal administration route may be …
down control of social attention. However, an oro-mucosal administration route may be …
The use of intranasal oxytocin in the treatment of eating disorders
M Malewska-Kasprzak, K Jowik, M Tyszkiewicz-Nwafor - Neuropeptides, 2023 - Elsevier
Oxytocin (OXT) is a hypothalamic peptide that plays a number of roles in the body, being
involved in labor and lactation, as well as cognitive-emotional processes and social …
involved in labor and lactation, as well as cognitive-emotional processes and social …
Oral oxytocin facilitates responses to emotional faces in reward and emotional-processing networks in females
Introduction: Oxytocin (OXT) is proposed as a potential therapeutic peptide for social
dysfunction due to its modulatory actions on socioemotional regulation in humans. While the …
dysfunction due to its modulatory actions on socioemotional regulation in humans. While the …