The role of high‐intensity focused ultrasound as a symptomatic treatment for Parkinson's disease

S Moosa, R Martínez‐Fernández, WJ Elias… - Movement …, 2019 - Wiley Online Library
MR‐guided focused ultrasound is a novel, minimally invasive surgical procedure for
symptomatic treatment of PD. With this technology, the ventral intermediate nucleus, STN …

The mechanisms of action of deep brain stimulation and ideas for the future development

K Udupa, R Chen - Progress in neurobiology, 2015 - Elsevier
Deep brain stimulation (DBS) has been used as a treatment of movement disorders such as
Parkinson's disease, dystonia, and essential tremor for over twenty years, and is a promising …

Adaptive deep brain stimulation for Parkinson's disease using motor cortex sensing

NC Swann, C De Hemptinne… - Journal of neural …, 2018 - iopscience.iop.org
Objective. Contemporary deep brain stimulation (DBS) for Parkinson's disease is delivered
continuously, and adjustments based on patient's changing symptoms must be made …

Parkinson Disease and Subthalamic Nucleus Deep Brain Stimulation: Cognitive Effects in GBA Mutation Carriers

G Pal, G Mangone, EJ Hill, B Ouyang, Y Liu… - Annals of …, 2022 - Wiley Online Library
Objective This study was undertaken to compare the rate of change in cognition between
glucocerebrosidase (GBA) mutation carriers and noncarriers with and without subthalamic …

Efficacy and safety of deep brain stimulation in Tourette syndrome: the international Tourette syndrome deep brain stimulation public database and registry

D Martinez-Ramirez, J Jimenez-Shahed… - JAMA …, 2018 - jamanetwork.com
Importance Collective evidence has strongly suggested that deep brain stimulation (DBS) is
a promising therapy for Tourette syndrome. Objective To assess the efficacy and safety of …

GPi vs STN deep brain stimulation for Parkinson disease: three-year follow-up

VJJ Odekerken, JA Boel, BA Schmand, RJ de Haan… - Neurology, 2016 - AAN Enterprises
Objective: To compare motor symptoms, cognition, mood, and behavior 3 years after deep
brain stimulation (DBS) of the globus pallidus pars interna (GPi) and subthalamic nucleus …

[HTML][HTML] Deep brain stimulation for movement disorders of basal ganglia origin: restoring function or functionality?

T Wichmann, MR DeLong - Neurotherapeutics, 2016 - Elsevier
Deep brain stimulation (DBS) is highly effective for both hypo-and hyperkinetic movement
disorders of basal ganglia origin. The clinical use of DBS is, in part, empiric, based on the …

Current applications and limitations of surgical treatments for movement disorders

P Krack, R Martinez‐Fernandez… - Movement …, 2017 - Wiley Online Library
Functional neurosurgery for the treatment of both psychiatric and neurological disorders has
been performed regularly since the 1940s. However, misuse in the early days and the …

Neuronal and synaptic adaptations underlying the benefits of deep brain stimulation for Parkinson's disease

W Xu, J Wang, XN Li, J Liang, L Song, Y Wu… - Translational …, 2023 - Springer
Deep brain stimulation (DBS) is a well-established and effective treatment for patients with
advanced Parkinson's disease (PD), yet its underlying mechanisms remain enigmatic …

The role of deep brain stimulation in Parkinson's disease: an overview and update on new developments

JY Fang, C Tolleson - Neuropsychiatric disease and treatment, 2017 - Taylor & Francis
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
loss of neuronal dopamine production in the brain. Oral therapies primarily augment the …