As opposed to acute respiratory infections, the persistent bacterial infections of the lung that
characterize cystic fibrosis (CF) provide ample time for bacteria to evolve and adapt. The …

Long-term infection of the airways of cystic fibrosis patients with Pseudomonas aeruginosa
is often accompanied by a reduction in bacterial growth rate. This reduction has been …

Pseudomonas aeruginosa (PA) is considered the first causal agent of morbidity and
mortality in people with cystic fibrosis (CF) disease. Multi-resistant strains have emerged due …

Heterotrophic Proteobacteria are versatile opportunists that have been extensively studied
as model organisms in the laboratory, as both pathogens and beneficial symbionts of plants …

Genetic background has the potential to influence both the tempo and trajectory of adaptive
change: Different genotypes of a given species may adopt varied solutions to the same …

Pseudomonas aeruginosa causes chronic airway infections, a major determinant of lung
inflammation and damage in cystic fibrosis (CF). Loss-of-function lasR mutants commonly …

The Pseudomonas aeruginosa genome can change to adapt to different ecological niches.
We compared four genomes from a Mexican hospital and 59 genomes from GenBank from …

Pseudomonas aeruginosa is a cause of chronic respiratory tract infections in people with
cystic fibrosis (CF), non-CF bronchiectasis, and chronic obstructive pulmonary disease …

Selective forces in the environment drive bacterial adaptation to novel niches, choosing the
fitter variants in the population. However, in dynamic and changing environments, the …

Objectives Pseudomonas aeruginosa colonizes the cystic fibrosis (CF) airways causing
chronic bacterial lung infections. CF patients are routinely treated with macrolides, however …