Prime editing: advances and therapeutic applications
Z Zhao, P Shang, P Mohanraju, N Geijsen - Trends in Biotechnology, 2023 - cell.com
Clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR–
Cas)-mediated genome editing has revolutionized biomedical research and will likely …
Cas)-mediated genome editing has revolutionized biomedical research and will likely …
Advances in CRISPR-based SERS detection of food contaminants: a review
Background The integration of CRISPR-Cas systems and surface-enhanced Raman
spectroscopy (SERS) has emerged as a powerful approach for developing highly sensitive …
spectroscopy (SERS) has emerged as a powerful approach for developing highly sensitive …
Viral Vectors for the in Vivo Delivery of CRISPR Components: Advances and Challenges
M Asmamaw Mengstie - Frontiers in Bioengineering and …, 2022 - frontiersin.org
The Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) and its
accompanying protein (Cas9) are now the most effective, efficient, and precise genome …
accompanying protein (Cas9) are now the most effective, efficient, and precise genome …
CRISPR-based genome editing for nutrient enrichment in crops: a promising approach toward global food security
The global malnutrition burden imparts long-term developmental, economic, social, and
medical consequences to individuals, communities, and countries. The current …
medical consequences to individuals, communities, and countries. The current …
Industrial applications of fungal lipases: a review
Fungal lipases (triacylglycerol acyl hydrolases EC 3.1. 1.3) are significant industrial
enzymes and have several applications in a number of industries and fields. Fungal lipases …
enzymes and have several applications in a number of industries and fields. Fungal lipases …
Gene editing therapeutics based on mRNA delivery
The field of gene editing has received much attention in recent years due to its immense
therapeutic potential. In particular, gene editing therapeutics, such as the CRISPR-Cas …
therapeutic potential. In particular, gene editing therapeutics, such as the CRISPR-Cas …
Viral vectors and extracellular vesicles: innate delivery systems utilized in CRISPR/Cas-mediated cancer therapy
Gene editing-based therapeutic strategies grant the power to override cell machinery and
alter faulty genes contributing to disease development like cancer. Nowadays, the principal …
alter faulty genes contributing to disease development like cancer. Nowadays, the principal …
Flourishing tumor organoids: History, emerging technology, and application
Q Yang, M Li, X Yang, Z Xiao, X Tong… - Bioengineering & …, 2023 - Wiley Online Library
Malignant tumors are one of the leading causes of death which impose an increasingly
heavy burden on all countries. Therefore, the establishment of research models that closely …
heavy burden on all countries. Therefore, the establishment of research models that closely …
CRISPR/Cas9 assisted stem cell therapy in Parkinson's disease
Since its discovery in 2012, CRISPR Cas9 has been tried as a direct treatment approach to
correct the causative gene mutation and establish animal models in neurodegenerative …
correct the causative gene mutation and establish animal models in neurodegenerative …
[HTML][HTML] Reduction of biofilm formation of Escherichia coli by targeting quorum sensing and adhesion genes using the CRISPR/Cas9-HDR approach, and its clinical …
M Alshammari, A Ahmad, M AlKhulaifi… - Journal of Infection and …, 2023 - Elsevier
Background Escherichia coli is a common cause of biofilm-associated urinary tract infections
(UTIs). Biofilm formation in E. coli is responsible for various indwelling medical device …
(UTIs). Biofilm formation in E. coli is responsible for various indwelling medical device …