Clinical phenotypes in heart failure with preserved ejection fraction
Over the past 2 decades, the syndrome of heart failure with preserved ejection fraction
(HFpEF) received a lot of attention. 1–19 However, little therapeutic progress was made. 20 …
(HFpEF) received a lot of attention. 1–19 However, little therapeutic progress was made. 20 …
Endomyocardial biopsy characterization of heart failure with preserved ejection fraction and prevalence of cardiac amyloidosis
Objectives This study prospectively evaluated endomyocardial biopsies in patients with
heart failure with preserved ejection fraction (HFpEF) to identify histopathologic phenotypes …
heart failure with preserved ejection fraction (HFpEF) to identify histopathologic phenotypes …
Myocardial gene expression signatures in human heart failure with preserved ejection fraction
Background: Heart failure (HF) with preserved ejection fraction (HFpEF) constitutes half of all
HF but lacks effective therapy. Understanding of its myocardial biology remains limited …
HF but lacks effective therapy. Understanding of its myocardial biology remains limited …
Cardiac microvascular endothelial enhancement of cardiomyocyte function is impaired by inflammation and restored by empagliflozin
The positive findings of the EMPA-REG OUTCOME trial (Randomized, Placebo-Controlled
Cardiovascular Outcome Trial of Empagliflozin) on heart failure (HF) outcome in patients …
Cardiovascular Outcome Trial of Empagliflozin) on heart failure (HF) outcome in patients …
[HTML][HTML] Targeting obesity and diabetes to treat heart failure with preserved ejection fraction
R Altara, M Giordano, ES Nordén, A Cataliotti… - Frontiers in …, 2017 - frontiersin.org
Heart failure with preserved ejection fraction (HFpEF) is a major unmet medical need that is
characterized by the presence of multiple cardiovascular and non-cardiovascular …
characterized by the presence of multiple cardiovascular and non-cardiovascular …
Heart failure increases the risk of adverse renal outcomes in patients with normal kidney function
LK George, SKG Koshy, MZ Molnar… - Circulation: Heart …, 2017 - Am Heart Assoc
Background Heart failure (HF) is associated with poor cardiac outcomes and mortality. It is
not known whether HF leads to poor renal outcomes in patients with normal kidney function …
not known whether HF leads to poor renal outcomes in patients with normal kidney function …
[HTML][HTML] Obesity, preserved ejection fraction heart failure, and left ventricular remodeling
J Stencel, HR Alai, A Dhore-Patil… - Journal of Clinical …, 2023 - mdpi.com
Owing to the overwhelming obesity epidemic, preserved ejection fraction heart failure
commonly ensues in patients with severe obesity and the obese phenotype of preserved …
commonly ensues in patients with severe obesity and the obese phenotype of preserved …
Randomized evaluation of heart failure with preserved ejection fraction patients with acute heart failure and dopamine: the ROPA-DOP trial
Objectives: This study sought to compare a continuous infusion diuretic strategy versus an
intermittent bolus diuretic strategy, with the addition of low-dose dopamine (3 μg/kg/min) in …
intermittent bolus diuretic strategy, with the addition of low-dose dopamine (3 μg/kg/min) in …
Prevalence of subclinical atrial fibrillation in heart failure with preserved ejection fraction
Background Atrial fibrillation (AF) is common in patients with heart failure with preserved
ejection fraction (HFpEF) and is associated with poorer clinical outcomes. The prevalence of …
ejection fraction (HFpEF) and is associated with poorer clinical outcomes. The prevalence of …
Predictors of mortality by sex and race in heart failure with preserved ejection fraction: ARIC community surveillance study
Background Heart failure with preserved ejection fraction (HFpEF) accounts for half of heart
failure hospitalizations, with limited data on predictors of mortality by sex and race. We …
failure hospitalizations, with limited data on predictors of mortality by sex and race. We …