Measurement of intramuscular oxygen could play a key role in the early diagnosis of acute
compartment syndrome, a common condition occurring after severe trauma leading to …

Objectives: Determine the intra-tidal regional gas and blood volume distributions at different
levels of atelectasis in experimental lung injury. Test the hypotheses that pulmonary aeration …

Background Within-breath oscillations in arterial oxygen tension (PaO2) can be detected
using fast responding intra-arterial oxygen sensors in animal models. These PaO2 signals …

The inspired sinewave technique (IST) is a non-invasive method to measure lung
heterogeneity indices (including both uneven ventilation and perfusion or heterogeneity) …

Background Real-time bedside information on regional ventilation and perfusion during
mechanical ventilation (MV) may help to elucidate the physiological and pathophysiological …

Acute respiratory distress syndrome (ARDS) is associated with a high rate of morbidity and
mortality, as patients undergoing mechanical ventilation are at risk of ventilator-induced lung …

Background Bedside lung volume measurement could personalise ventilation and reduce
driving pressure in patients with acute respiratory distress syndrome (ARDS). We …

Background Bedside measurement of lung volume may provide guidance in the
personalised setting of respiratory support, especially in patients with the acute respiratory …

Background Dynamic single-slice CT (dCT) is increasingly used to examine the intra-tidal,
physiological variation in aeration and lung density in experimental lung injury. The ability of …

The inspired sinewave technique (IST) is a non-invasive nonionising method which can
measure accurately lung parameters. Six anaesthetised pigs were studied after surfactant …