Cervical cancer immunotherapy: facts and hopes

L Ferrall, KY Lin, RBS Roden, CF Hung, TC Wu - Clinical Cancer Research, 2021 - AACR
It is a sad fact that despite being almost completely preventable through human
papillomavirus (HPV) vaccination and screening, cervical cancer remains the fourth most …

HPV post-infection microenvironment and cervical cancer

Y Yuan, X Cai, F Shen, F Ma - Cancer Letters, 2021 - Elsevier
Human papillomavirus (HPV) is the most common sexually transmitted virus worldwide.
More than 99% of cervical cancer cases are associated with certain types of HPVs, termed …

A current update on human papillomavirus-associated head and neck cancers

E Tumban - Viruses, 2019 - mdpi.com
Human papillomavirus (HPV) infection is the cause of a growing percentage of head and
neck cancers (HNC); primarily, a subset of oral squamous cell carcinoma, oropharyngeal …

Acquired resistance to cancer immunotherapy: Role of tumor-mediated immunosuppression

R Saleh, E Elkord - Seminars in cancer biology, 2020 - Elsevier
In the tumor microenvironment (TME), tumor cells are constantly evolving to reduce
neoantigen generation and the mutational burden to escape the anti-tumor response. This …

Development of DNA vaccine targeting E6 and E7 proteins of human papillomavirus 16 (HPV16) and HPV18 for immunotherapy in combination with recombinant …

S Peng, L Ferrall, S Gaillard, C Wang, WY Chi… - MBio, 2021 - Am Soc Microbiol
Immunotherapy for cervical cancer should target high-risk human papillomavirus types 16
and 18, which cause 50% and 20% of cervical cancers, respectively. Here, we describe the …

Design of a multi-epitope vaccine against cervical cancer using immunoinformatics approaches

S Sanami, F Azadegan-Dehkordi… - Scientific Reports, 2021 - nature.com
Cervical cancer, caused by human papillomavirus (HPV), is the fourth most common type of
cancer among women worldwide. While HPV prophylactic vaccines are available, they have …

Development of therapeutic vaccines for the treatment of diseases

Y Tian, D Hu, Y Li, L Yang - Molecular Biomedicine, 2022 - Springer
Vaccines are one of the most effective medical interventions to combat newly emerging and
re-emerging diseases. Prophylactic vaccines against rabies, measles, etc., have excellent …

Advances in designing and developing vaccines, drugs and therapeutic approaches to counter human papilloma virus

M Dadar, S Chakraborty, K Dhama, M Prasad… - Frontiers in …, 2018 - frontiersin.org
Human papillomavirus (HPV) is a viral infection with skin-to-skin based transmission mode.
HPV annually caused over 500,000 cancer cases including cervical, anogenital and …

The Interaction of Human Papillomavirus Infection and Prostaglandin E2 Signaling in Carcinogenesis: A Focus on Cervical Cancer Therapeutics

J García-Quiroz, B Vázquez-Almazán… - Cells, 2022 - mdpi.com
Chronic infection by high-risk human papillomaviruses (HPV) and chronic inflammation are
factors associated with the onset and progression of several neoplasias, including cervical …

Vaccination strategies for the control and treatment of HPV infection and HPV-associated cancer

E Farmer, MA Cheng, CF Hung, TC Wu - Viruses and Human Cancer …, 2021 - Springer
Human papillomavirus (HPV) is the most common sexually transmitted infection, currently
affecting close to 80 million Americans. Importantly, HPV infection is recognized as the …