For a select number of drugs, proper management of patients includes monitoring serum or
plasma concentrations of the drugs and adjusting the doses accordingly–this practice is …

The surface proteins of parasitic protozoa mediate functions essential to survival within a
host, including nutrient accumulation, environmental sensing and immune evasion. Several …

Purpose Suramin, a polysulfonated naphthylurea, inhibits the actions of polypeptide growth
factors including acidic and basic fibroblast growth factors (aFGF and bFGF), which confer …

Purpose In preclinical models, non-cytotoxic suramin (concentrations< 50 μM) potentiates
the activity of multiple chemotherapeutic agents. The present study evaluated the safety and …

Background: To assess the value of plasma vitamin D level and nomogram model in
predicting the prognosis of patients with small cell lung cancer (SCLC) treated with platinum …

Purpose: The objective is to analyze the antiangiogenic mechanism of suramab, a
pharmaceutical compound of bevacizumab and suramin, in a rabbit model of corneal …

Background Renal cell carcinoma (RCC) is recognized as a neoplasm resistant to
chemotherapy. In vitro experiments demonstrated that suramin, at noncytotoxic doses …

Laboratory scientists in cancer research typically focus on unraveling the molecular basis of
carcinogenesis, identifying novel cellular and molecular targets for interventions, and …

(57) ABSTRACT A method for determining a therapeutically effective amount of Suramin for
administering to a patient, who is to receive a cytotoxic agent, which comprises the steps of …

Translational research bridges preclinical and clinical research and shortens distance
between these two areas in biomedical research. In preclinical study, our laboratory has …