Selenium species: current status and potentials in cancer prevention and therapy

HW Tan, HY Mo, ATY Lau, YM Xu - International journal of molecular …, 2018 - mdpi.com
Selenium (Se) acts as an essential trace element in the human body due to its unique
biological functions, particularly in the oxidation-reduction system. Although several clinical …

Understanding selenium metabolism in plants and its role as a beneficial element

R Chauhan, S Awasthi, S Srivastava… - Critical Reviews in …, 2019 - Taylor & Francis
Selenium (Se) is an essential element for many animals including humans, prokaryotes and
a few green algae. For plants, Se essentiality is yet to be demonstrated. Nevertheless, it is …

[HTML][HTML] Selenium nanoparticles: Synthesis, in-vitro cytotoxicity, antioxidant activity and interaction studies with ct-DNA and HSA, HHb and Cyt c serum proteins

N Shahabadi, S Zendehcheshm, F Khademi - Biotechnology Reports, 2021 - Elsevier
The aim of this study was the synthesis of selenium nanoparticles (SeNPs) employing
vitamin C as a biocompatible and low toxic reducing agent. The synthesized selenium …

Selenium biofortification: Strategies, progress and challenges

OP Danso, B Asante-Badu, Z Zhang, J Song, Z Wang… - Agriculture, 2023 - mdpi.com
Selenium (Se) is an essential trace element for humans and animals. Its necessity for plants
is still under examination. Due to the contradictory nature of Se and its significance, it has …

Mechanisms of the cytotoxic effect of selenium nanoparticles in different human cancer cell lines

EG Varlamova, MV Goltyaev, VN Mal'tseva… - International journal of …, 2021 - mdpi.com
In recent decades, studies on the functional features of Se nanoparticles (SeNP) have
gained great popularity due to their high biocompatibility, stability, and pronounced …

Triple Cross‐linked Dynamic Responsive Hydrogel Loaded with Selenium Nanoparticles for Modulating the Inflammatory Microenvironment via PI3K/Akt/NF‐κB and …

S Wang, Y Liu, Q Sun, B Zeng, C Liu, L Gong… - Advanced …, 2023 - Wiley Online Library
Modulating the inflammatory microenvironment can inhibit the process of inflammatory
diseases (IDs). A tri‐cross‐linked inflammatory microenvironment‐responsive hydrogel with …

The innovative potential of selenium-containing agents for fighting cancer and viral infections

W Ali, R Benedetti, J Handzlik, C Zwergel… - Drug Discovery …, 2021 - Elsevier
Selenium-containing compounds have emerged as a potentially promising treatment for
viral infections and tumor development and dissemination. Selenium per se is often …

Selenium as a pleiotropic agent for medical discovery and drug delivery

B Guan, R Yan, R Li, X Zhang - International journal of …, 2018 - Taylor & Francis
Selenium as a biologically active element lends much support to health maintenance and
disease prevention. It is now presenting pleiotropic effects on therapy and drug delivery. In …

[HTML][HTML] Design, synthesis and anticancer evaluation of novel Se-NSAID hybrid molecules: Identification of a Se-indomethacin analog as a potential therapeutic for …

S Ramos-Inza, I Encío, A Raza, AK Sharma… - European journal of …, 2022 - Elsevier
A total of twenty-five novel carboxylic acid, methylester, methylamide or cyano nonsteroidal
anti-inflammatory drug (NSAID) derivatives incorporating Se in the chemical form of …

Selenium and dopamine-crosslinked hyaluronic acid hydrogel for chemophotothermal cancer therapy

M Yang, SY Lee, S Kim, JS Koo, JH Seo… - Journal of Controlled …, 2020 - Elsevier
Sodium selenite (Se)-directed crosslinked hydrogels based on hyaluronic acid (HA)-
dopamine (HD), including indocyanine green (ICG), were developed for local therapy of …