A review on phosphodiesterase-5 inhibitors as a topical therapy for erectile dysfunction
M Hamzehnejadi, M Ranjbar Tavakoli… - Sexual Medicine …, 2022 - academic.oup.com
Introduction Due to the prevalence of erectile dysfunction and impotence among men in
recent years, several pharmacotherapies have been considered for such problems …
recent years, several pharmacotherapies have been considered for such problems …
[HTML][HTML] Non-arteritic anterior ischemic optic neuropathy associated with the use of phosphodiesterase type 5 inhibitors: a literature review
M Hor, AM Baradeiya, H Qasim, M Nasr, A Mohammad - Cureus, 2022 - ncbi.nlm.nih.gov
Abstract Phosphodiesterase type 5 (PDE5) inhibitors are frequently used for erectile
dysfunction (ED) as the first line of treatment. This medication was initially developed to treat …
dysfunction (ED) as the first line of treatment. This medication was initially developed to treat …
[HTML][HTML] Eleutheroside B ameliorated high altitude pulmonary edema by attenuating ferroptosis and necroptosis through Nrf2-antioxidant response signaling
Y Wang, Z Shen, C Pei, S Zhao, N Jia, D Huang… - Biomedicine & …, 2022 - Elsevier
High altitude pulmonary edema (HAPE) is a potentially fatal condition induced by exposure
to high-altitude environment. Eleutheroside B is a naturally active polyphenolic substance …
to high-altitude environment. Eleutheroside B is a naturally active polyphenolic substance …
[HTML][HTML] The weekend drug; recreational use of sildenafil citrate and concomitant factors: a cross-sectional study
BW Atsbeha, BT Kebede, BS Birhanu… - Frontiers in …, 2021 - frontiersin.org
Background: Men who use erectile dysfunction medications for recreational purposes may
be at increased risk of becoming psychologically dependent, which in turn could lead to …
be at increased risk of becoming psychologically dependent, which in turn could lead to …
[HTML][HTML] Sildenafil, a phosphodiesterase-5 inhibitor, stimulates angiogenesis and bone regeneration in an atrophic non-union model in mice
MM Menger, D Bauer, M Bleimehl, C Scheuer… - Journal of Translational …, 2023 - Springer
Non-union formation represents a major complication in trauma and orthopedic surgery. The
phosphodiesterase-5 (PDE-5) inhibitor sildenafil has been shown to exert pro-angiogenic …
phosphodiesterase-5 (PDE-5) inhibitor sildenafil has been shown to exert pro-angiogenic …
Recreational use of oral PDE5 inhibitors: the other side of midnight
T Mostafa, MF Alghobary - Sexual Medicine Reviews, 2022 - academic.oup.com
ABSTRACT Background Nowadays, Oral phosphodiesterase type 5 inhibitors (PDE5Is) are
widely used for the treatment of erectile dysfunction (ED). However, these drugs have …
widely used for the treatment of erectile dysfunction (ED). However, these drugs have …
[HTML][HTML] Ganoderma lucidum polysaccharide ameliorated diabetes mellitus-induced erectile dysfunction in rats by regulating fibrosis and the NOS/ERK/JNK pathway
X Yao, Y Yuan, T Jing, S Ye, S Wang… - … Andrology and Urology, 2022 - ncbi.nlm.nih.gov
Background Diabetes mellitus-induced erectile dysfunction (DMED) is a frequent
complication of diabetes mellitus (DM), with limited therapy at present. This study aimed to …
complication of diabetes mellitus (DM), with limited therapy at present. This study aimed to …
[PDF][PDF] Contribution of phosphodiesterase-5 (PDE5) inhibitors in the various diseases
S Kumar, M Kulshreshtha, S Saha, S Shankar… - Int J Sci Healthc …, 2022 - inrein.com
ABSTRACT The PDE-5 inhibitors, ie, phosphodiesterase-5 inhibitors like sildenafil,
vardenafil, and tadalafil, are the most used in premature erectile dysfunction. Many literature …
vardenafil, and tadalafil, are the most used in premature erectile dysfunction. Many literature …
[HTML][HTML] Azithromycin and Sildenafil May Have Protective Effects on Retinal Ganglion Cells via Different Pathways: Study in a Rodent Microbead Model
TC Sela, A Zahavi, M Friedman-Gohas, S Weiss… - Pharmaceuticals, 2023 - mdpi.com
Decreased blood flow to the optic nerve (ON) and neuroinflammation are suggested to play
an important role in the pathophysiology of glaucoma. This study investigated the potential …
an important role in the pathophysiology of glaucoma. This study investigated the potential …
Role of interaction mode of phenanthrene derivatives as selective PDE5 inhibitors using molecular dynamics simulations and quantum chemical calculations
S Sainimnuan, A Chimprasit, S Hannongbua… - Molecular Diversity, 2024 - Springer
Abstract Phosphodiesterase type 5 (PDE5) inhibitors play a crucial role in blocking PDE5 to
improve erectile dysfunction (ED). However, most PDE5 drugs revealed side effects …
improve erectile dysfunction (ED). However, most PDE5 drugs revealed side effects …