Expansion of the Clostridium perfringens toxin-based typing scheme

JI Rood, V Adams, J Lacey, D Lyras, BA McClane… - Anaerobe, 2018 - Elsevier
Clostridium perfringens causes many different histotoxic and enterotoxic diseases in
humans and animals as a result of its ability to produce potent protein toxins, many of which …

Zoonotic diseases of fish and their prevention and control

M Ziarati, MJ Zorriehzahra, F Hassantabar… - Veterinary …, 2022 - Taylor & Francis
Fish and aquatic-derived zoonotic diseases have caused considerable problems in the
aquaculture industry and fishery worldwide. In particular, zoonotic diseases can pose …

Pathogenicity and virulence of Clostridium perfringens

I Mehdizadeh Gohari, M A. Navarro, J Li, A Shrestha… - Virulence, 2021 - Taylor & Francis
Clostridium perfringens is an extremely versatile pathogen of humans and livestock, causing
wound infections like gas gangrene (clostridial myonecrosis), enteritis/enterocolitis …

Enteric pathogens and their toxin-induced disruption of the intestinal barrier through alteration of tight junctions in chickens

WA Awad, C Hess, M Hess - Toxins, 2017 - mdpi.com
Maintaining a healthy gut environment is a prerequisite for sustainable animal production.
The gut plays a key role in the digestion and absorption of nutrients and constitutes an initial …

Mechanisms of Action and Cell Death Associated with Clostridium perfringens Toxins

MA Navarro, BA McClane, FA Uzal - Toxins, 2018 - mdpi.com
Clostridium perfringens uses its large arsenal of protein toxins to produce histotoxic,
neurologic and intestinal infections in humans and animals. The major toxins involved in …

Alternatives to antibiotics to prevent necrotic enteritis in broiler chickens: a microbiologist's perspective

DL Caly, R D'Inca, E Auclair, D Drider - Frontiers in microbiology, 2015 - frontiersin.org
Since the 2006 European ban on the use of antibiotics as growth promoters in animal feed,
numerous studies have been published describing alternative strategies to prevent diseases …

Unraveling the role of vegetables in spreading antimicrobial-resistant bacteria: a need for quantitative risk assessment

CS Hölzel, JL Tetens, K Schwaiger - Foodborne pathogens and …, 2018 - liebertpub.com
In recent years, vegetables gain consumer attraction due to their reputation of being healthy
in combination with low energy density. However, since fresh produce is often eaten raw, it …

Avian Pathogenic Escherichia coli and Clostridium perfringens: Challenges in No Antibiotics Ever Broiler Production and Potential Solutions

CA Fancher, L Zhang, AS Kiess, PA Adhikari, TTN Dinh… - Microorganisms, 2020 - mdpi.com
United States is the largest producer and the second largest exporter of broiler meat in the
world. In the US, broiler production is largely converting to antibiotic-free programs which …

Clostridium perfringens Enterotoxin: Action, Genetics, and Translational Applications

JC Freedman, A Shrestha, BA McClane - Toxins, 2016 - mdpi.com
Clostridium perfringens enterotoxin (CPE) is responsible for causing the gastrointestinal
symptoms of several C. perfringens food-and nonfood-borne human gastrointestinal …

Large clostridial toxins: mechanisms and roles in disease

KE Orrell, RA Melnyk - Microbiology and Molecular Biology …, 2021 - Am Soc Microbiol
Large clostridial toxins (LCTs) are a family of bacterial exotoxins that infiltrate and destroy
target cells. Members of the LCT family include Clostridioides difficile toxins TcdA and TcdB …