Glaucoma treatment trends: a review

R Conlon, H Saheb, IIK Ahmed - Canadian Journal of Ophthalmology, 2017 - Elsevier
Glaucoma is one of the most common causes of blindness worldwide, and its prevalence is
increasing. The aim of the present review is to describe the current medical and surgical …

Extraocular, periocular, and intraocular routes for sustained drug delivery for glaucoma

UB Kompella, RR Hartman, MA Patil - Progress in retinal and eye research, 2021 - Elsevier
Although once daily anti-glaucoma drug therapy is a current clinical reality, most therapies
require multiple dosing and there is an unmet need to develop convenient, safe, and …

Pharmacotherapy of glaucoma

D Schmidl, L Schmetterer, G Garhöfer… - Journal of Ocular …, 2015 - liebertpub.com
Glaucoma is a group of diseases involving the optic nerve and associated structures, which
is characterized by progressive visual field loss and typical changes of the optic nerve head …

Medical management of glaucoma in the 21st century from a Canadian perspective

P Harasymowycz, C Birt, P Gooi… - Journal of …, 2016 - Wiley Online Library
Glaucoma is a medical term describing a group of progressive optic neuropathies
characterized by degeneration of retinal ganglion cells and retinal nerve fibre layer and …

Therapeutic drugs and devices for tackling ocular hypertension and glaucoma, and need for neuroprotection and cytoprotective therapies

NA Sharif - Frontiers in pharmacology, 2021 - frontiersin.org
Damage to the optic nerve and the death of associated retinal ganglion cells (RGCs) by
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …

Fixed-dose combination of netarsudil and latanoprost in ocular hypertension and open-angle glaucoma: pooled efficacy/safety analysis of phase 3 MERCURY-1 and …

S Asrani, J Bacharach, E Holland, H McKee… - Advances in …, 2020 - Springer
Introduction New open-angle glaucoma (OAG) and ocular hypertension (OHT) therapies that
reduce treatment burden and improve outcomes relative to currently available agents are …

Simultaneous co-delivery of neuroprotective drugs from multi-loaded PLGA microspheres for the treatment of glaucoma

A Arranz-Romera, BM Davis, I Bravo-Osuna… - Journal of Controlled …, 2019 - Elsevier
Glaucoma is a multifactorial neurodegenerative disorder and one of the leading causes of
irreversible blindness globally and for which intraocular pressure is the only modifiable risk …

New glaucoma medications: latanoprostene bunod, netarsudil, and fixed combination netarsudil-latanoprost

NA Mehran, S Sinha, R Razeghinejad - Eye, 2020 - nature.com
Reduction of intraocular pressure is the only proven method to treat glaucoma. Initial
treatment of glaucoma commonly involves using anti-glaucoma medications either as …

The Japan Glaucoma Society guidelines for glaucoma 5th edition

Y Kiuchi, T Inoue, N Shoji, M Nakamura… - Japanese Journal of …, 2023 - Springer
We are pleased to bring you the 5th edition of the Glaucoma Clinical Practice Guidelines.
Clinical practice guidelines are based on evidence (scientific grounds). It is a document that …

FP and EP2 prostanoid receptor agonist drugs and aqueous humor outflow devices for treating ocular hypertension and glaucoma

NA Sharif, N Odani-Kawabata, F Lu… - Experimental Eye …, 2023 - Elsevier
Prostaglandin (PG) receptors represent important druggable targets due to the many diverse
actions of PGs in the body. From an ocular perspective, the discovery, development, and …