Objectives To set parameters for clinical diagnosis, to evaluate severity, and to standardize
treatment, maintenance, and monitoring options for chronic myeloid leukemia (CML) …

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm caused by BCR–ABL, a
constitutively active tyrosine kinase generated as a result of the t (9; 22)(q34; q11). The …

Background: This document includes recommendations and guidelines issued by a group of
Mexican researchers and specialists gathered in the First National Colloquium for the …

Approximately 10%–12% of patients in chronic-phase chronic myeloid leukemia (CP-CML)
have additional chromosomal aberrations at diagnosis; moreover, CML occurs in up to 10 …

Background: Analysis of Philadelphia (Ph) chromosome, a hallmark of chronic myeloid
leukemia (CML) plays an important role in disease monitoring of the targeted drug Imatinib …

摘要目的: 观察国产甲磺酸伊马替尼片治疗慢性粒细胞白血病(CML) 患者的疗效及安全性. 方法:
选取CML 患者16 例, 其中初诊CML 即给予甲磺酸IM 治疗者7 例, 诊断CML 超过12 …

Abstract In 5–10% of cases with CML, variant or complex translocations (CT) are seen that
may result in atypical fluorescence in situ hybridization signal patterns. Dual color, dual …

Telling the story of the advances in chronic myeloid leukemia (CML), seen from a historical
perspective, one cannot deny the extraordinary role of cytogenetics. When John Hughes …

Chronic myeloid leukemia (CML) is characterized by the presence of the Philadelphia
chromosome (Ph), which results from a balanced translocation between chromosomes 9 …

Chronic myeloid leukaemia (CML) was the first leukaemia associated with a unique genetic
abnormality, the Philadelphia chromosome. This results from a reciprocal translocation …