[HTML][HTML] The roles of extracellular vesicles in the immune system
EI Buzas - Nature Reviews Immunology, 2023 - nature.com
The twenty-first century has witnessed major developments in the field of extracellular
vesicle (EV) research, including significant steps towards defining standard criteria for the …
vesicle (EV) research, including significant steps towards defining standard criteria for the …
[HTML][HTML] The exosome journey: from biogenesis to uptake and intracellular signalling
S Gurung, D Perocheau, L Touramanidou… - Cell Communication and …, 2021 - Springer
The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
[HTML][HTML] Exploiting the biogenesis of extracellular vesicles for bioengineering and therapeutic cargo loading
J Rädler, D Gupta, A Zickler, SEL Andaloussi - Molecular Therapy, 2023 - cell.com
Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …
applications in various diseases. These natural nanoparticles benefit from favorable safety …
[HTML][HTML] The role of cancer-associated fibroblasts in cancer invasion and metastasis
PJ Asif, C Longobardi, M Hahne, JP Medema - Cancers, 2021 - mdpi.com
Simple Summary Cancer metastasis is often associated with a dismal prognosis for the
patient. It is, therefore, crucial to understand the mechanisms behind the cascade of events …
patient. It is, therefore, crucial to understand the mechanisms behind the cascade of events …
[HTML][HTML] Extracellular vesicles: mediators of intercellular communication in tissue injury and disease
G Berumen Sánchez, KE Bunn, HH Pua… - Cell Communication and …, 2021 - Springer
Intercellular communication is a critical process that ensures cooperation between distinct
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …
[HTML][HTML] Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling
F Xie, X Zhou, P Su, H Li, Y Tu, J Du, C Pan… - Nature …, 2022 - nature.com
Cancer immunotherapies have shown clinical success in various types of tumors but the
patient response rate is low, particularly in breast cancer. Here we report that malignant …
patient response rate is low, particularly in breast cancer. Here we report that malignant …
Basophil activation test: mechanisms and considerations for use in clinical trials and clinical practice
AF Santos, O Alpan, HJ Hoffmann - Allergy, 2021 - Wiley Online Library
The basophil activation test (BAT) is a functional assay that measures the degree of
degranulation following stimulation with allergen or controls by flow cytometry. It correlates …
degranulation following stimulation with allergen or controls by flow cytometry. It correlates …
[HTML][HTML] Exosome-derived microRNAs of human milk and their effects on infant health and development
BC Melnik, W Stremmel, R Weiskirchen, SM John… - Biomolecules, 2021 - mdpi.com
Multiple biologically active components of human milk support infant growth, health and
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
[HTML][HTML] Advances in analysis of biodistribution of exosomes by molecular imaging
Exosomes are nano-sized membranous vesicles produced by nearly all types of cells. Since
exosome-like vesicles are produced in an evolutionarily conserved manner for information …
exosome-like vesicles are produced in an evolutionarily conserved manner for information …
The tissue origin effect of extracellular vesicles on cartilage and bone regeneration
Q Li, H Yu, M Sun, P Yang, X Hu, Y Ao, J Cheng - Acta Biomaterialia, 2021 - Elsevier
Direct implantation of mesenchymal stem cells (MSCs) for cartilage and bone tissue
engineering faces challenges, such as immune rejection and loss of cellular viability or …
engineering faces challenges, such as immune rejection and loss of cellular viability or …