Introduction: Neuropathic pain affects up to 8% of the population with few therapeutic
options for its management. No specific drugs are approved for its treatment. Areas covered …

This paper is the 29th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning 30 years of research. It summarizes papers …

A series of benzene sulfonamide carbonic anhydrase (CA, EC 4.2. 1.1) inhibitors which
incorporate lipophilic 4-alkoxy-and 4-aryloxy moieties, together with several derivatives of …

Pharmacology of peripheral opioid receptors : Current Opinion in Anesthesiology
Pharmacology of peripheral opioid receptors : Current Opinion in Anesthesiology Log in or …

NSAIDs represent some of the most widely prescribed drugs for relief of short-term fever,
pain and inflammation. The participation of the opioid system in the peripheral is poorly …

Ethnopharmacological relevance Extracts of the stem bark of Ficus platyphylla (FP) have
been used in traditional the Nigerian medicine to treat psychoses, depression, epilepsy …

Endogenous opioids have been implicated in compound-induced antinociception, and our
group previously suggested that xylazine induces peripheral antinociception by releasing …

The earliest stages of osteoarthritis are characterized by peripheral pathology; however,
during disease progression chronic pain emerges—a major symptom of osteoarthritis linked …

Background Cimicoxib is a new coxib anti-inflammatory drug for use in the dog. To
determine a preclinical dosage regimen for cimicoxib in dog, a reversible model of kaolin …

Abstract Background/Aims: In this study we analyzed the mechanisms underlying celecoxib-
induced analgesia in a model of inflammatory pain in rats, using the intracerebroventricular …