Life Below the Gum Line: Pathogenic Mechanisms ofPorphyromonas gingivalis

RJ Lamont, HF Jenkinson - Microbiology and molecular biology …, 1998 - Am Soc Microbiol
Porphyromonas gingivalis, a gram-negative anaerobe, is a major etiological agent in the
initiation and progression of severe forms of periodontal disease. An opportunistic pathogen …

Fibronectin: a multidomain host adhesin targeted by bacterial fibronectin-binding proteins

B Henderson, S Nair, J Pallas… - FEMS microbiology …, 2011 - academic.oup.com
Fibronectin, a large and essential multidomain glycoprotein, with multiple adhesive
properties, functioning as a key link between cells and their extracellular matrices, is now …

Involvement of integrins in fimbriae‐mediated binding and invasion by Porphyromonas gingivalis

Ö Yilmaz, K Watanabe, RJ Lamont - Cellular microbiology, 2002 - Wiley Online Library
Interaction between the major fimbriae of Porphyromonas gingivalis and gingival epithelial
cells is important for bacterial adhesion and invasion. In this study, we identified integrins as …

Role of fibronectin-binding MSCRAMMs in bacterial adherence and entry into mammalian cells

D Joh, ER Wann, B Kreikemeyer, P Speziale, M Höök - Matrix Biology, 1999 - Elsevier
Most bacterial infections are initiated by the adherence of microorganisms to host tissues.
This process involves the interaction of specific bacterial surface structures, called adhesins …

[HTML][HTML] Porphyromonas gingivalis FimA and Mfa1 fimbriae: Current insights on localization, function, biogenesis, and genotype

Y Hasegawa, K Nagano - Japanese Dental Science Review, 2021 - Elsevier
In general, the periodontal pathogen Porphyromonas gingivalis expresses distinct FimA and
Mfa1 fimbriae. Each of these consists of five FimA–E and five Mfa1–5 proteins encoded by …

The importance of fimbriae in the virulence and ecology of some oral bacteria

S Hamada, A Amano, S Kimura… - Oral microbiology …, 1998 - Wiley Online Library
Cumulative evidence indicates that bacterial adherence to mucosal and tooth surfaces as
well as bacterial coaggregation are essential steps for colonization of various oral bacterial …

Bacterial adhesion to animal tissues: protein determinants for recognition of extracellular matrix components

C Chagnot, A Listrat, T Astruc… - Cellular …, 2012 - Wiley Online Library
The extracellular matrix (ECM) is present within all animal tissues and organs. Actually, it
surrounds the eukaryotic cells composing the four basic tissue types, ie epithelial, muscle …

[PDF][PDF] Engagement of specific innate immune signaling pathways during Porphyromonas gingivalis induced chronic inflammation and atherosclerosis

G FC III - Front. Biosci., 2008 - article.imrpress.com
Introduction 3. Epidemiological Associations Of Infection With Systemic Diseases 3.1.
Infectious Agents And Association With Atherosclerosis 3.2. Periodontal Disease And P …

Identification and characterization of a novel fibronectin-binding protein on the surface of group A streptococci

CL Rocha, VA Fischetti - Infection and immunity, 1999 - Am Soc Microbiol
Understanding the role surface proteins play in the interaction of group A streptococci with
epithelial cells is an important step toward the development of new strategies to fight …

Heterogeneity of Porphyromonas gingivalis strains in the induction of alveolar bone loss in mice

PJ Baker, M Dixon, RT Evans… - Oral microbiology and …, 2000 - Wiley Online Library
These experiments examine alveolar bone loss in a model in which specific pathogen‐free
mice are exposed orally with Porphyromonas gingivalis. Alveolar bone loss was induced as …