Elesclomol is an anticancer drug that targets mitochondrial metabolism. In the past,
elesclomol was recognized as an inducer of oxidative stress, but now it has also been found …

Initiation and development of cancer depend on multiple factors that mutations in genes and
epigenetic level can be considered as important drivers. Epigenetic factors include a large …

Among the different kinds of tumors threatening human life, lung cancer is one that is
commonly observed in both males and females. The aggressive behavior of lung cancer …

Ovarian cancer (OC) is a malignant tumor that seriously threatens women's health. Due to
the difficulty of early diagnosis, most patients exhibit advanced disease or peritoneal …

Nowadays, the combined use of chemotherapy and photodynamic therapy (PDT) remains
the most popular strategy for cancer treatment with high theraprutic efficacy. However …

Chromosomal instability (CIN) is a hallmark of cancer and is associated with tumor cell
malignancy. CIN triggers a chain reaction in cells leading to chromosomal abnormalities …

A series of hetero-dinuclear Ru–Os complexes have been constructed by combining
mononuclear modules derived from homo-dinuclear Ru–Ru complexes with dual PDT/PTT …

To overcome the resistance of tumour cells to cis-diaminedichloroplatinum (II)(cisplatin,
DDP), we designed and synthesised platinum (II) complexes with copper coordination active …

Lung cancer is the leading cause of cancer‑related mortality worldwide. Non‑small cell lung
cancer (NSCLC) is the most common pathological subtype of lung cancer and is associated …

Background Certain antineoplastic drugs cause gastrointestinal disorders even after the end
of treatment. Enteric neuropathy has been associated with some of these alterations. Our …