[HTML][HTML] Reactive oxygen species and ovarian diseases: Antioxidant strategies

J Liang, Y Gao, Z Feng, B Zhang, Z Na, D Li - Redox Biology, 2023 - Elsevier
Reactive oxygen species (ROS) are mainly produced in mitochondria and are involved in
various physiological activities of the ovary through signaling and are critical for regulating …

[HTML][HTML] Coping with oxidative stress in reproductive pathophysiology and assisted reproduction: Melatonin as an emerging therapeutical tool

P Cosme, AB Rodríguez, M Garrido, J Espino - Antioxidants, 2022 - mdpi.com
Infertility is an increasing global public health concern with socio-psychological implications
for affected couples. Remarkable advances in reproductive medicine have led to successful …

[HTML][HTML] PCOS and role of cumulus gene expression in assessing oocytes quality

N Sayutti, MA Abu, MF Ahmad - Frontiers in Endocrinology, 2022 - frontiersin.org
The global infertility rate has been declining from year to year. PCOS is one of the treatable
accountable causes contributing to anovulatory infertility. Nevertheless, the success rate of …

[HTML][HTML] Melatonin attenuates oxidative stress-induced apoptosis of bovine ovarian granulosa cells by promoting mitophagy via SIRT1/FoxO1 signaling pathway

G Xu, Y Dong, Z Wang, H Ding, J Wang, J Zhao… - International Journal of …, 2023 - mdpi.com
Oxidative-stress-induced apoptosis of granulosa cells is considered to be a main driver of
follicular atresia. Increasing evidence suggests a protective effect of melatonin against …

[HTML][HTML] Effects of n-3 PUFA supplementation on oocyte in vitro maturation in mice with polycystic ovary syndrome

R Ma, S Wang, M Xue, H Zhang, Z He… - Journal of Ovarian …, 2023 - Springer
Abstract n-3 PUFAs are classic antioxidant that can be used to treat follicular dysplasia and
hyperinsulinemia caused by excessive oxidative stress in PCOS women. To investigate the …

[HTML][HTML] Melatonin Supplementation during In Vitro Maturation of Porcine Oocytes Alleviates Oxidative Stress and Endoplasmic Reticulum Stress Induced by …

J Wang, XQ Wang, RP Liu, YH Li, XR Yao, NH Kim… - Animals, 2023 - mdpi.com
Simple Summary The residue of chemicals can affect the maturation of livestock oocytes,
thereby affecting the quality of embryos. Research has shown that imidacloprid, a systemic …

[HTML][HTML] Distinct characteristics of the DNA damage response in mammalian oocytes

J Leem, C Lee, DY Choi, JS Oh - Experimental & Molecular Medicine, 2024 - nature.com
DNA damage is a critical threat that poses significant challenges to all cells. To address this
issue, cells have evolved a sophisticated molecular and cellular process known as the DNA …

The protective effects of astaxanthin on pre-antral follicle degeneration in ovine vitrified/warmed ovarian tissue

A Afzali, H Nazari, E Ahmadi, F Amidi, F Taheri… - Cryobiology, 2023 - Elsevier
This study assesses the protective effects of astaxanthin (AST) against vitrification/warming-
induced cryoinjuries of ovarian tissue slices in sheep. Cortical slices of slaughterhouse …

[HTML][HTML] Integration of parallel metabolomics and transcriptomics reveals metabolic patterns in porcine oocytes during maturation

M Gao, M Chen, Q Chen, S Zhu, H Wang… - Frontiers in …, 2023 - frontiersin.org
Well-controlled metabolism is the prerequisite for optimal oocyte development. To date,
numerous studies have focused mainly on the utilization of exogenous substrates by …

[HTML][HTML] The effect of altered Mucin1, FGF2, and HBEGF gene expression at the ectopic implantation site and endometrial tissues in the tubal pregnancy pathogenesis …

N Noghrehalipour, R Aflatoonian… - … Journal of Fertility & …, 2023 - ncbi.nlm.nih.gov
Background: Ectopic pregnancy (EP) is defined as implantation and development of an
embryo outside of the uterine tissue. Women undergoing assisted reproductive technologies …