Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

The brain is worthy of study because it is in charge of behavior. A flurry of recent technical
advances in measuring and quantifying naturalistic behaviors provide an important …

Long-lasting internal arousal states motivate and pattern ongoing behaviour, enabling the
temporary emergence of innate behavioural programs that serve the needs of an animal …

Internal states shape stimulus responses and decision-making, but we lack methods to
identify them. To address this gap, we developed an unsupervised method to identify …

What are the spatial and temporal scales of brainwide neuronal activity? We used swept,
confocally-aligned planar excitation (SCAPE) microscopy to image all cells in a large …

In the Drosophila brain,'compass' neurons track the orientation of the body and head (the
fly's heading) during navigation,. In the absence of visual cues, the compass neuron network …

Goal-directed social behaviours such as mating and fighting are associated with scalable
and persistent internal states of emotion, motivation, arousal or drive. How those internal …

Accurately predicting an outcome requires that animals learn supporting and conflicting
evidence from sequential experience. In mammals and invertebrates, learned fear …

Assigning behavioral functions to neural structures has long been a central goal in
neuroscience and is a necessary first step toward a circuit-level understanding of how the …

Principles of Neurobiology, Second Edition presents the major concepts of neuroscience
with an emphasis on how we know what we know. The text is organized around a series of …