Genetic landscape and biomarkers of hepatocellular carcinoma

J Zucman-Rossi, A Villanueva, JC Nault, JM Llovet - Gastroenterology, 2015 - Elsevier
Hepatocellular carcinoma (HCC) has emerged as a major cause of cancer-related death. Its
mortality has increased in Western populations, with a minority of patients diagnosed at …

Pathogenic mechanisms in HBV-and HCV-associated hepatocellular carcinoma

A Arzumanyan, HM Reis, MA Feitelson - Nature Reviews Cancer, 2013 - nature.com
Hepatocellular carcinoma (HCC) is a highly lethal cancer, with increasing worldwide
incidence, that is mainly associated with chronic hepatitis B virus (HBV) and/or hepatitis C …

EASL–EORTC clinical practice guidelines: management of hepatocellular carcinoma

European Association For The Study Of … - Journal of …, 2012 - journal-of-hepatology.eu
EASL–EORTC Clinical Practice Guidelines (CPG) on the management of hepatocellular
carcinoma (HCC) define the use of surveillance, diagnosis, and therapeutic strategies …

[HTML][HTML] EASL–EORTC clinical practice guidelines: management of hepatocellular carcinoma

EO for Research… - Journal of …, 2012 - Elsevier
EASL–EORTC Clinical Practice Guidelines (CPG) on the management of hepatocellular
carcinoma (HCC) define the use of surveillance, diagnosis, and therapeutic strategies …

[PDF][PDF] NANOG metabolically reprograms tumor-initiating stem-like cells through tumorigenic changes in oxidative phosphorylation and fatty acid metabolism

CL Chen, DBU Kumar, V Punj, J Xu, L Sher, SM Tahara… - Cell metabolism, 2016 - cell.com
Stem cell markers, including NANOG, have been implicated in various cancers; however,
the functional contribution of NANOG to cancer pathogenesis has remained unclear. Here …

[HTML][HTML] Targeting Wnt/β-catenin pathway in hepatocellular carcinoma treatment

V Vilchez, L Turcios, F Marti… - World journal of …, 2016 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related death
worldwide. Liver cancer is generally related to hepatitis B or C infection and cirrhosis …

Chemotherapy for hepatocellular carcinoma: current status and future perspectives

M Ikeda, C Morizane, M Ueno… - Japanese journal of …, 2018 - academic.oup.com
Chemotherapy is one of the most important treatment modalities for advanced
hepatocellular carcinoma (HCC). On the basis of the results of two pivotal Phase III placebo …

Current strategy for staging and treatment: the BCLC update and future prospects

A Forner, ME Reig, CR de Lope… - Seminars in liver …, 2010 - thieme-connect.com
Staging and treatment indication are relevant topics in the management of patients with
hepatocellular carcinoma (HCC) and for optimal results, they have to take into account liver …

Functional and genetic deconstruction of the cellular origin in liver cancer

JU Marquardt, JB Andersen, SS Thorgeirsson - Nature Reviews Cancer, 2015 - nature.com
During the past decade, research on primary liver cancers has particularly highlighted the
uncommon plasticity of differentiated parenchymal liver cells (that is, hepatocytes and …

Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma

Y Hoshida, SMB Nijman, M Kobayashi, JA Chan… - Cancer research, 2009 - AACR
Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, and prior attempts to
develop genomic-based classification for HCC have yielded highly divergent results …