Background Islet transplantation offers an effective treatment for selected people with type 1
diabetes and intractable hypoglycaemia. Long-term experience, however, remains limited …

Islet transplantation is a highly effective treatment for select patients with type 1 diabetes.
Unfortunately, current use is limited to those with brittle disease due to donor limitations and …

Update on islet cell transplantation : Current Opinion in Organ Transplantation Update on islet
cell transplantation : Current Opinion in Organ Transplantation Log in or Register Subscribe to …

Background. Preliminary studies show promise for extrahepatic islet transplantation (ITx).
However, clinical comparisons with intraportal ITx outcomes remain limited. Methods. This …

Objective: To provide the largest single-center analysis of islet (ITx) and pancreas (PTx)
transplantation. Summary Background Data: Studies describing long-term outcomes with ITx …

The apoptosis of grafted islets is an urgent problem due to the high rate of islet loss soon
after transplantation. MicroRNA-21-5p (miR-21-5p) is an essential mediator of bone marrow …

Since every biological system requires capillaries to support its oxygenation, design of
engineered preclinical models of such systems, for example, vascularized …

ABSTRACT Introduction 'Brittle Diabetes'(BD) is a life-threatening metabolic complication
after total pancreatectomy (TP). More than 500 Intraportal islet autotransplantation (IAT) …

Type 1 diabetes mellitus (T1DM) is an autoimmune condition that results in the destruction of
insulin-secreting β cells of the islets of Langerhans. Allogeneic islet transplantation could be …

The pathogenesis of diabetes mellitus is characterized by insulin resistance and islet β-cell
dysfunction. Up to now, the focus of diabetes treatment has been to control blood glucose to …