Uncovering the true burden of hereditary angioedema due to C1-inhibitor deficiency: a focus on the Asia-Pacific region

D Honda, PH Li, AK Jindal, CH Katelaris, YX Zhi… - Journal of Allergy and …, 2023 - Elsevier
Hereditary angioedema (HAE) due to C1-inhibitor (C1-INH) deficiency or dysfunction is a
rare genetic disorder that causes recurrent episodes of swelling in various parts of the body …

[HTML][HTML] Management of hereditary angioedema in resource-constrained settings: A consensus statement from Indian subcontinent

AK Jindal, A Sil, R Aggarwal, K Vinay… - Asia Pacific …, 2023 - journals.lww.com
Hereditary angioedema (HAE) is an uncommon disorder characterized clinically by
recurrent episodes of nonitchy subcutaneous and/or submucosal swellings. The estimated …

[HTML][HTML] Hong Kong–Macau Severe Hives and Angioedema Referral Pathway

PH Li, EYL Au, SL Cheong, L Chung, KI Fan… - Frontiers in …, 2023 - frontiersin.org
Background Urticaria (defined as the presence of hives, angioedema, or both) can be
caused by a variety of etiologies ranging from more common conditions such as chronic …

[HTML][HTML] Clinical utility of and correlation between Sniffin'Sticks and TIB smell identification test (TIBSIT) among Hong Kong Chinese with or without chronic …

HWF Mak, SY Ho, JCY Wong, V Chiang, E Lee… - Frontiers in …, 2024 - frontiersin.org
Introduction Olfactory dysfunction (OD) is common among patients with chronic
rhinosinusitis (CRS). Validated and culturally specific tests, such as the “Sniffin'Sticks” test …

[HTML][HTML] Screening for type II hereditary angioedema—the “poor man's c1-inhibitor function”

AK Jindal, V Chiang, P Barman, A Sil, S Chawla… - Journal of Allergy and …, 2024 - Elsevier
Background Hereditary angioedema (HAE) is a rare genetic disease. Patients with type II
HAE have normal or elevated C1-inhibitor (C1-INH) levels but C1-INH protein is …

[HTML][HTML] Long-term prophylaxis for hereditary angioedema: Initial experiences with garadacimab and lanadelumab

JCY Wong, V Chiang, DLY Lam, E Lee, K Lam… - Journal of Allergy and …, 2023 - Elsevier
Background With no approved long-term prophylaxis (LTP) for the prevention of hereditary
angioedema (HAE) attacks in Hong Kong, patients rely on compassionate use programs …

[HTML][HTML] Real-world experience of hereditary angioedema (HAE) in Mexico: A mixed-methods approach to describe epidemiology, diagnosis, and treatment patterns

S Nieto, I Madrigal, F Contreras, ME Vargas - World Allergy Organization …, 2023 - Elsevier
Introduction and objectives Due to the lack of structured and systematic information
available, the aim of this study was to describe the epidemiology, diagnosis, healthcare …

Hereditary and Acquired Angioedema for Rheumatologists in India: Are We Missing the Diagnosis?

S Basu, R Tyagi, S Machhua… - Indian Journal of …, 2024 - journals.sagepub.com
Bradykinin-mediated angioedema can broadly be categorised into hereditary angioedema
(HAE) and acquired angioedema (AAE). Both HAE and AAE are grossly under-recognised …

[PDF][PDF] Results from a randomized, double-blind, placebo-controlled, phase 1 trial evaluating sebetralstat pharmacokinetics, pharmacodynamics, and safety/tolerability …

M Hide, M Iverson, S Jhee, E Hansen, EJ Duckworth… - ALLERGY, 2023 - kalvista.com
Conclusions• Sebetralstat PK, PD, and safety profiles were comparable in healthy
Japanese, Chinese, and White adults• Near-complete (≥ 95% geometric mean) inhibition of …

[HTML][HTML] A new journey of Asia Pacific Allergy

R Pawankar, L Zhang - Asia Pacific Allergy, 2023 - journals.lww.com
The Asia Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI) is the
regional allergy organization of Asia Pacific. It aims to advance impact and communicate all …