Objective One of the most critical reasons for limiting cancer treatment is the toxic effects of
anti-cancer drugs on healthy tissues and organs. This study aims to investigate the possible …

We investigated the hepato-protective effects of thymoquinone (TQ) and beta-
aminoisobutyric acid (BAIBA). We used five groups of 8-week-old male rats: untreated …

The present study investigated the protective effect of misoprostol (MSP)(0.2 mg/kg, oral)
against kidney injury caused by paclitaxel (PLX)(2 mg/kg, intraperitoneal) in female Sprague …

Diabetic cardiomyopathy (DCM) is a cardiac dysfunction observed in a patient with diabetes
that may lead to heart failure. No specific treatment has yet been tested in DCM. Therefore …

The effects of drugs used in cancer treatment are not only specific to cancer cells but also
negatively affect healthy cells. This study, it was aimed to investigate the protective effects of …

The main objective of our study was to examine the protection of misoprostol (MP) on
paclitaxel (PAX) side effects in rat brains. Twenty-eight female Sprague-Dawley rats were …

Diabetes mellitus is known as the “epidemic of the century” due to its global prevalence.
Several pre-clinical and clinical studies have shown that male germ cell toxicity is one of the …

The success of chemotherapy regimens has led to an increase in cancer survival rate over
the last decades. Melphalan has been widely used for the treatment of several types of …

Massive proteinuria, oedema, hypoalbuminemia, and hyperlipidemia are the hallmarks of
nephrotic syndrome (NS). Recently, epigenetic pathways in renal diseases have been …

La neuropatía diabética (DN) es una complicación diabética crónica, que es difícil de
manejar. La presente investigación evalúa el efecto de Nerium oleander (NO) en el …