Osteoimmune regulation underlies oral implant osseointegration and its perturbation

T Albrektsson, P Tengvall, L Amengual, P Coli… - Frontiers in …, 2023 - frontiersin.org
In the field of biomaterials, an endosseous implant is now recognized as an
osteoimmunomodulatory but not bioinert biomaterial. Scientific advances in bone cell …

Innovative surface modification procedures to achieve micro/nano-graded Ti-based biomedical alloys and implants

J Li, P Zhou, S Attarilar, H Shi - Coatings, 2021 - mdpi.com
Due to the growing aging population of the world, and as a result of the increasing need for
dental implants and prostheses, the use of titanium and its alloys as implant materials has …

[HTML][HTML] Stimuli-responsive metal–organic framework hydrogels endow long carbon fiber reinforced polyetheretherketone with enhanced anti-inflammatory and …

W Dong, S Zhao, Y Wang, X Zhou, J Jiang, J Dang… - Materials & Design, 2023 - Elsevier
The ideal orthopedic implant has sufficient biomechanical strength and physiological activity
to coordinate with the intricate physiological healing process of the tissue. Herein …

YAP‐Suppressive Nanodrug Crosslinked Self‐Immunoregulatory Polysaccharide Injectable Hydrogel for Attenuating Cardiac Fibrosis to Treat Myocardial Infarction

Y Sun, X Zhang, T Wu, Z Zhang… - Advanced Functional …, 2023 - Wiley Online Library
The cardiac fibrosis caused by excessive deposition of collagen and the fibro‐inflammatory
cascade reaction severely impedes the cardiac regenerative efficiency after myocardial …

An Amorphous Peri‐Implant Ligament with Combined Osteointegration and Energy‐Dissipation

J Hou, Z Xiao, Z Liu, H Zhao, Y Zhu, L Guo… - Advanced …, 2021 - Wiley Online Library
Progress toward developing metal implants as permanent hard‐tissue substitutes requires
both osteointegration to achieve load‐bearing support, and energy‐dissipation to prevent …

Trace element-augmented titanium implant with targeted angiogenesis and enhanced osseointegration in osteoporotic rats

R Yan, J Li, Q Wu, X Zhang, L Hu, Y Deng… - Frontiers in …, 2022 - frontiersin.org
Deteriorated bone quality in osteoporosis challenges the success of implants, which are in
urgent need for better early osseointegration as well as antibacterial property for long-term …

Incorporation of inorganic elements onto titanium-based implant surfaces by one-step plasma electrolytic oxidation: an efficient method to enhance osteogenesis

T Huang, H Wang, Z Zhang, K Feng, L Xiang - Biomaterials Science, 2022 - pubs.rsc.org
In the field of dental and orthopedic implantation, the core issue is achieving good and
stable osseointegration rapidly as well as for long-term, which is associated with a series of …

[HTML][HTML] The Hippo pathway: a renewed insight in the craniofacial diseases and hard tissue remodeling

J Chen, J Cheng, C Zhao, B Zhao, J Mi… - International Journal of …, 2021 - ncbi.nlm.nih.gov
The Hippo pathway plays an important role in many pathophysiological processes, including
cell proliferation and differentiation, cell death, cell migration and invasion. Because of its …

Verteporfin attenuates trauma‐induced heterotopic ossification of Achilles tendon by inhibiting osteogenesis and angiogenesis involving YAP/β‐catenin signaling

G Luo, Z Sun, H Liu, Z Yuan, W Wang, B Tu… - The FASEB …, 2023 - Wiley Online Library
Heterotopic ossification occurs as a pathological ossification condition characterized by
ectopic bone formation within soft tissues following trauma. Vascularization has long been …

YAP/TAZ: Molecular pathway and disease therapy

Y Wei, VLZ Hui, Y Chen, R Han, X Han, Y Guo - MedComm, 2023 - Wiley Online Library
The Yes‐associated protein and its transcriptional coactivator with PDZ‐binding motif
(YAP/TAZ) are two homologous transcriptional coactivators that lie at the center of a key …