Overlapping mechanisms of action of brain-active bacteria and bacterial metabolites in the pathogenesis of common brain diseases

TP Eicher, MH Mohajeri - Nutrients, 2022 - mdpi.com
The involvement of the gut microbiota and the metabolites of colon-residing bacteria in brain
disease pathogenesis has been covered in a growing number of studies, but comparative …

The state of the art on acetylcholinesterase inhibitors in the treatment of Alzheimer's disease

I Vecchio, L Sorrentino, A Paoletti… - Journal of Central …, 2021 - journals.sagepub.com
Alzheimer's disease (AD) is a chronic disabling disease that affects the central nervous
system. The main consequences of AD include the decline of cognitive functions and …

Molecular targets of natural compounds with anti-cancer properties

M Kubczak, A Szustka, M Rogalińska - International Journal of Molecular …, 2021 - mdpi.com
Cancer is the second leading cause of death in humans. Despite rapid developments in
diagnostic methods and therapies, metastasis and resistance to administrated drugs are the …

[HTML][HTML] A large-scale causal analysis of gut microbiota and delirium: a Mendelian randomization study

H Yu, X Wan, M Yang, J Xie, K Xu, J Wang… - Journal of Affective …, 2023 - Elsevier
Background Several studies have linked gut microbiota to human brain activity. This study
used Mendelian randomization (MR) to investigate the causal relationship between gut …

The crosstalk between gut microbiota and nervous system: a bidirectional interaction between microorganisms and metabolome

M Montagnani, L Bottalico, MA Potenza… - International Journal of …, 2023 - mdpi.com
Several studies have shown that the gut microbiota influences behavior and, in turn,
changes in the immune system associated with symptoms of depression or anxiety disorder …

Activation of aryl hydrocarbon receptor (AhR) in Alzheimer's disease: Role of tryptophan metabolites generated by gut host-microbiota

A Salminen - Journal of Molecular Medicine, 2023 - Springer
Gut microbiota in interaction with intestinal host tissues influences many brain functions and
microbial dysbiosis has been linked with brain disorders, such as neuropsychiatric …

Periodontitis-related salivary microbiota aggravates Alzheimer's disease via gut-brain axis crosstalk

J Lu, S Zhang, Y Huang, J Qian, B Tan, X Qian… - Gut …, 2022 - Taylor & Francis
The oral cavity is the initial chamber of digestive tract; the saliva swallowed daily contains an
estimated 1.5× 1012 oral bacteria. Increasing evidence indicates that periodontal pathogens …

Curcumin nanoformulations to combat aging-related diseases

M Mahjoob, U Stochaj - Ageing Research Reviews, 2021 - Elsevier
Aging increases the susceptibility to a diverse set of diseases and disorders, including
neurodegeneration, cancer, diabetes, and arthritis. Natural compounds are currently being …

Recent developments in the probiotics as live biotherapeutic products (LBPs) as modulators of gut brain axis related neurological conditions

D Ağagündüz, F Gençer Bingöl, E Çelik… - Journal of Translational …, 2022 - Springer
Probiotics have been defined as “living microorganisms that create health benefits in the
host when taken in sufficient amounts. Recent developments in the understanding of the …

[HTML][HTML] The health effect of probiotics on high-fat diet-induced cognitive impairment, depression and anxiety: A cross-species systematic review

J Lof, K Smits, V Melotte, LE Kuil - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Obesity is a complex disease with many co-morbidities, including impaired cognitive
functions. Obese individuals often contain an aberrant microbiota. Via the microbiota-gut …