Inflammasomes are newly recognized, vital players in innate immunity. The best
characterized is the NLRP3 inflammasome, so-called because the NLRP3 protein in the …

The inflammasome is a cytoplasmic protein complex that processes interleukins (IL)-1β and
IL-18, and drives a form of cell death known as pyroptosis. Oligomerization of this complex is …

The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin
domain-containing 3 (NLRP3) inflammasome is a member of the NLR family of inherent …

Innate sensors play a critical role in the early innate immune responses to invading
pathogens through sensing of diverse biochemical signatures also known as pathogen …

The NLRP3 (nucleotide-binding oligomerization domain-like receptor [NLR] family pyrin
domain-containing 3) inflammasome is a member of the NLR family of innate immune cell …

Inflammation is a devastating pathophysiological process during stroke, a devastating
disease that is the second most common cause of death worldwide. Activation of the NOD …

The NLRP3 inflammasome is a caspase‐1‐containing multi‐protein complex that controls
the release of IL‐1β and plays important roles in the development of inflammatory disease …

Reproduction involves tightly regulated series of events and the immune system is involved
in an array of reproductive processes. Disruption of well-controlled immune functions leads …

Inflammasomes are multi-protein complexes composed of a NOD-like receptor (NLR)/an
AIM-like receptor (ALR), the adapter molecule apoptosis-associated speck-like protein that …

Aberrant activation of NLRP3 inflammasome has been implicated in the pathogenesis of
diverse inflammation-related diseases, and pharmacological molecules targeting NLRP3 …