Familial Hypercholesterolaemia in Children and Adolescents: Current and Future Perspectives

F Martino, F Barilla, E Martino… - Current Pediatric …, 2023 - ingentaconnect.com
Familial hypercholesterolemia (FH) is a genetic disease, the underlying cause of which is
represented by mutations capable of influencing the metabolism of low-density lipoproteins …

An evidence gap map of interventions for noncommunicable diseases and risk factors among children and adolescents

RA Salam, MH Khan, SSA Meerza, JK Das… - Nature Medicine, 2024 - nature.com
Substance misuse, obesity, mental health conditions, type 1 diabetes, cancers, and
cardiovascular and chronic respiratory diseases together account for 41% of disability …

Apoliprotein C-III (Apo C-III) inhibitors effect of antisense oligonucleotides in the management of dyslipidemia

IGAP Sasmana, PNK Rahadi, AAT Devy… - Indonesia Journal of …, 2023 - ijbs-udayana.org
Introduction: Dyslipidemia is an abnormal condition of blood lipid levels with a global
prevalence of 31.2% which can cause various complications including atherosclerosis that …

Antiobesity and antidyslipidemic properties of Clitoria ternatea petals aqueous extract against rats induced by high-fat diet

I Sasmana, DM WIHANDANI, I Sadeva… - Turkish Journal of …, 2024 - journals.tubitak.gov.tr
Background/aim: Obesity is a chronic metabolic disease involving dysregulation of fat
metabolism that affects 13% of the world's population. Obesity has been linked to …

Investigating the Incidence of Dyslipidemia among Brazilian Children and Adolescents Diagnosed with Type 1 Diabetes Mellitus: A Cross-Sectional Study

R Fagundes Melo, LF Laurindo, KP Sloan, LA Sloan… - Diseases, 2024 - mdpi.com
The treatment of Type 1 Diabetes Mellitus (T1DM) has always been a challenge for health
professionals in relation to glycemic control. Increased body fat has been related to a …

Enhancing Pharmacokinetics and Pharmacodynamics of Rosuvastatin Calcium through the Development and Optimization of Fast-Dissolving Films

I Ashraf, PA Hanna, S Gad, FI Abd-Allah, KM El-Say - Pharmaceutics, 2023 - mdpi.com
Rosuvastatin (RSV) is a widely used cholesterol-lowering medication, but its limited
bioavailability due to its susceptibility to stomach pH and extensive first-pass metabolism …

Correlation of Vitamin 25 (OH) D, Liver Enzymes, Potassium, and Oxidative Stress Markers with Lipid Profile and Atheromatic Index: A Pilot Study

S Ioannidou, K Kazeli, H Ventouris, D Amanatidou… - Journal of …, 2023 - mdpi.com
According to recent literature, there is a limited amount of data about the correlation of
vitamin 25 (OH) D, potassium (K), oxidative stress parameters, and other biomarkers with …

Comparison of Two Strategies for Hypercholesterolemia Detection through Point-of-Care Testing

HE Arriaga-Cázares, D Vega-Morales… - Diagnostics, 2024 - mdpi.com
Background: Childhood dyslipidemia is a common condition that can lead to atherosclerotic
cardiovascular disease in adulthood. It is usually multifactorial. Screening for cholesterol …

Plasma lipids paediatric reference intervals: Indirect estimation using a large 14‐year database

P Galozzi, A Padoan, C Moretti, A Aita… - Journal of Pediatric …, 2024 - Wiley Online Library
Objectives Establishing direct reference intervals (RIs) for paediatric patients is a very
challenging endeavour. Indirect RIs can address this problem, using existing clinical …

MiRNA-122 as a biomarker for insulin resistance and risk of cardiovascular diseases in obese children

SM Abdou, AM Abd El-Maksoud, GF Ahmed… - Gene Reports, 2024 - Elsevier
Background Obesity in children is a major worldwide concern that has several negative
health consequences in both the short and long term. The objective of this study was to …