Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …

Background Cancer is the most prevalent cause of death globally, and radiotherapy is
considered the standard of care for most solid tumors, including lung, breast, esophageal …

Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

MicroRNAs (miRNAs) are short, noncoding RNAs that regulate gene expression by
suppressing mRNA translation and reducing mRNA stability. A miRNA can potentially bind …

Simple Summary Apoptosis, a programmed form of cell death, represents the main
mechanism by which cells die. Such phenomenon is highly regulated by the BCL-2 family of …

Pomegranate peel, derived from the processing of Punica granatum L.(pomegranate), has
traditionally been considered agricultural waste. However, recent studies have revealed its …

Benzimidazole, the benzo derivative of imidazole, is a class of bicyclic aromatic organic
compound consisting of six‐membered benzene ring fused to five‐membered imidazole at 4 …

Abstract Tripartite motif 17 (TRIM17) belongs to a subfamily of the RING-type E3 ubiquitin
ligases, and regulates several cellular processes and pathological conditions including …

In the current study, fennel essential oil was used as an antibiotic alternative compared to
gentamycin for enhancing the expression of apoptosis genes and antioxidant enzymes in …

How cytochrome C is released from the mitochondria to the cytosol via Bax oligomeric
pores, a process which is required for apoptosis, is still a mystery. Based on experimentally …