The planar cell polarity (PCP) pathway controls a variety of morphological events across
many species. During embryonic development, the PCP pathway regulates coordinated …

Chronic wounds constitute a significant and growing biomedical burden. With the increasing
growth of populations prone to dysfunctional wound healing, there is an urgent and unmet …

Hybridization is a natural or anthropogenic process that can deeply affect the genetic make-
up of populations, possibly decreasing individual fitness but sometimes favoring local …

Despite the immense progress in genetics and cell biology, major knowledge gaps remain
with respect to prediction and control of the global morphologies that will result from the …

The skin is the largest organ of the human body, composed of a diverse range of cell types,
non-cellular components, and an extracellular matrix. With aging, molecules that are part of …

The primary cilium is essential for skin morphogenesis through regulating the Notch, Wnt,
and hedgehog signaling pathways. Prior studies on the functions of primary cilia in the skin …

Variation in regional identity, patterning, and structure of epidermal appendages contributes
to skin diversity among many vertebrate groups, and is perhaps most striking in birds. In …

Reaction–diffusion models have been used as a paradigm for describing the de novo
emergence of biological patterns such as stripes and spots. In many organisms, these initial …

In normal condition human hair growth occurs through three phases, anagen (growth phase
included about 85% of hairs, last from 2 to 6 years), catagen (transitional phase lasting up to …

Much remains unknown about the regulatory networks which govern the dermal papilla's
(DP) ability to induce hair follicle neogenesis, a capacity which decreases greatly with age …