Chronic inflammation and immune responses are two core element that characterize the
tumor microenvironment. A large number of immune/inflammatory cells (including tumor …

Simple Summary The tumor microenvironment (TME) in breast cancer plays important roles
in tumor behavior and treatment response, making its pathologic assessment critical for …

Owing to high antibiotic resistance and thermotolerance, bacterial biofilm infections (BBIs)
are refractory to elimination. Iron is essential for bacterial growth and metabolism, and …

Tracking the immune microenvironment of tumours is essential for understanding the
mechanisms behind the effectiveness of cancer immunotherapies. Molecular imaging of …

Hepatocellular carcinoma (HCC) commonly emerges in an immunologically “cold” state,
thereafter protects it away from cytolytic attack by tumor‐infiltrating lymphocytes, resulting in …

Neutrophil extracellular traps (NETs) consist of decondensed nuclear chromatin that is
associated with proteins and are released by neutrophils during an inflammatory response …

The inducible nitric oxide signaling (iNOS) pathway is associated with poor prognosis in
triple-negative breast cancer (TNBC). Prior studies using in vivo models showed that …

Chemokines are a group of about 50 chemotactic cytokines crucial for the migration of
immune system cells and tumor cells, as well as for metastasis. One of the 20 chemokine …

Human papillomavirus (HPV)-associated cervical cancer is a leading cause of cancer
deaths in women. Here we present an integrated multi-omic analysis of 643 cervical …

Pancreatic cancer is a deadly disease with little response to standard therapies. Irreversible
electroporation (IRE) has emerged as a novel ablative technique for the clinical treatment of …