The discovery that aggregated transactive response DNA-binding protein 43 kDa (TDP-43)
is the major component of pathological ubiquitinated inclusions in amyotrophic lateral …

Introduction: Several neuroimaging techniques have been used to define in vivo markers of
pathological alterations underlying amyotrophic lateral sclerosis (ALS). Growing evidence …

Neuropathology and neuroanatomy of TDP-43 amyotrophic latera... : Current Opinion in
Neurology Neuropathology and neuroanatomy of TDP-43 amyotrophic lateral sclerosis …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. However, no reliable
biomarkers have been identified to represent the clinical status. This study aimed to …

MRI and PET studies in ALS have consistently shown patterns of functional and structural
changes considered to be the pathological signature of the disease. The constant advance …

The development of new possible treatments for C9orf72-related ALS and the possibility of
early identification of subjects genetically at risk of developing the disease is creating a …

Background: With the advances in neuroimaging in amyotrophic lateral sclerosis (ALS), it
has been speculated that multiparametric magnetic resonance imaging (MRI) is capable to …

ObjectiveAdvanced neuroimaging techniques may offer the potential to monitor disease
progression in amyotrophic lateral sclerosis (ALS), a neurodegenerative, multisystem …

Background and purpose This study sought to evaluate the relationship of progressive
corticospinal tract (CST) degeneration with survival in patients with amyotrophic lateral …

Introduction Within the core neuroimaging signature of amyotrophic lateral sclerosis (ALS),
the corpus callosum (CC) is increasingly recognized as a consistent feature. The aim of this …