Photoreceptor cells and RPE contribute to the development of diabetic retinopathy
D Tonade, TS Kern - Progress in retinal and eye research, 2021 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness. It has long been regarded as
vascular disease, but work in the past years has shown abnormalities also in the neural …
vascular disease, but work in the past years has shown abnormalities also in the neural …
[HTML][HTML] Genome editing in the treatment of ocular diseases
Genome-editing technologies have ushered in a new era in gene therapy, providing novel
therapeutic strategies for a wide range of diseases, including both genetic and nongenetic …
therapeutic strategies for a wide range of diseases, including both genetic and nongenetic …
[HTML][HTML] In vivo imaging of the human eye using a 2-photon-excited fluorescence scanning laser ophthalmoscope
J Boguslawski, G Palczewska… - The Journal of …, 2022 - Am Soc Clin Investig
Background Noninvasive assessment of metabolic processes that sustain regeneration of
human retinal visual pigments (visual cycle) is essential to improve ophthalmic diagnostics …
human retinal visual pigments (visual cycle) is essential to improve ophthalmic diagnostics …
[PDF][PDF] Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia
In daylight, demand for visual chromophore (11-cis-retinal) exceeds supply by the classical
visual cycle. This shortfall is compensated, in part, by the retinal G-protein-coupled receptor …
visual cycle. This shortfall is compensated, in part, by the retinal G-protein-coupled receptor …
From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation
G Palczewska, M Wojtkowski, K Palczewski - Progress in retinal and eye …, 2023 - Elsevier
The eye is an ideal organ for imaging by a multi-photon excitation approach, because ocular
tissues such as the sclera, cornea, lens and neurosensory retina, are highly transparent to …
tissues such as the sclera, cornea, lens and neurosensory retina, are highly transparent to …
Optogenetic strategies for high-efficiency all-optical interrogation using blue-light-sensitive opsins
All-optical methods for imaging and manipulating brain networks with high spatial resolution
are fundamental to study how neuronal ensembles drive behavior. Stimulation of neuronal …
are fundamental to study how neuronal ensembles drive behavior. Stimulation of neuronal …
Benchmarking two-photon absorption strengths of rhodopsin chromophore models with CC3 and CCSD methodologies: An assessment of popular density functional …
S Sirimatayanant, T Andruniów - The Journal of Chemical Physics, 2023 - pubs.aip.org
This work presents the investigations of the impact of an increasing electron correlation in
the hierarchy of coupled-cluster methods, ie, CC2, CCSD, and CC3, on two-photon …
the hierarchy of coupled-cluster methods, ie, CC2, CCSD, and CC3, on two-photon …
In situ autofluorescence lifetime assay of a photoreceptor stimulus response in mouse retina and human retinal organoids
K Samimi, BR Pattnaik, EE Capowski… - Biomedical Optics …, 2022 - opg.optica.org
Photoreceptors are the key functional cell types responsible for the initiation of vision in the
retina. Phototransduction involves isomerization and conversion of vitamin A compounds …
retina. Phototransduction involves isomerization and conversion of vitamin A compounds …
Laser-induced deformation and fragmentation of droplets in an array
Droplet–droplet interactions is ubiquitous in various applications ranging from medical
diagnostics to enhancing and optimizing liquid jet propulsion. We employ an experimental …
diagnostics to enhancing and optimizing liquid jet propulsion. We employ an experimental …
Secondary cavitation bubble dynamics during laser-induced bubble formation in a small container
We investigated secondary cavitation bubble dynamics during laser-induced bubble
formation in a small container with a partially confined free surface and elastic thin walls. We …
formation in a small container with a partially confined free surface and elastic thin walls. We …