determination and the implementation of preventive, diagnostic or therapeutic medical
strategies. However, the ESC Guidelines do not override in any way whatsoever the …

Objective The objective of this study was to provide guidance on the use of the Grading of
Recommendations Assessment, Development and Evaluation (GRADE) approach to …

In February 2022, these guidelines were reviewed by an expert work group convened by
ASH. Review included limited searches for new evidence and discussion of the search …

The task of developing ESC Guidelines covers not only the integration of the most recent
research, but also the creation of educational tools and implementation programmes for the …

Importance D-dimer measurement is an important step in the diagnostic strategy of clinically
suspected acute pulmonary embolism (PE), but its clinical usefulness is limited in elderly …

Background: Acute aortic syndromes (AASs) are rare and severe cardiovascular
emergencies with unspecific symptoms. For AASs, both misdiagnosis and overtesting are …

Pulmonary embolism is the third most common cause of death from cardiovascular disease
after heart attack and stroke. Sequelae occurring after venous thromboembolism include …

Description: Pulmonary embolism (PE) can be a severe disease and is difficult to diagnose,
given its nonspecific signs and symptoms. Because of this, testing patients with suspected …

Document Reviewers: Jose-Luis Zamorano,(CPG Review Coordinator)(Spain), Felicita
Andreotti (Italy), Michael Ascherman (Czech Republic), George Athanassopoulos (Greece) …

Background The accuracy of multidetector computed tomographic angiography (CTA) for the
diagnosis of acute pulmonary embolism has not been determined conclusively. Methods …