Purpose Prostaglandins play a critical role in cervical ripening by increasing inflammatory
mediators in the cervix and inducing cervical remodeling. Prostaglandin E1 (PGE1) and …

Pyometra is a common reproductive disorder which affects nearly one fourth of all female
dogs before they reach 10 y of age. An association between pyometra and the most …

Ovine artificial insemination (OAI) is not commonly performed because of specific problems
related to semen application techniques, leading to highly variable results. The ideal …

Successful pregnancy necessitates that the uterus is maintained in a relaxed, quiescent
state for the majority of pregnancy, before being transformed to a contractile and excitable …

Transcervical artificial insemination in sheep is limited by the inability to completely
penetrate the cervix with an inseminating pipette. Penetration is partially enhanced at estrus …

Reactive Oxygen Species (ROS) are produced during oxidative metabolism, and regulate
many biological processes. The acute inflammation characterizing parturition induces many …

Prostaglandins (PGs) are necessary for normal female reproduction. PGs act via their
respective receptors and execute various functions in their target tissues depending on …

The mechanisms of cervical ripening and dilation in mammals remain obscure. Information
is lacking about the localization of prostaglandin E2 (PGE2)-producing cells and PGE2 …

The aim of this study was to determine which PGE 2 receptors (EP 1–4 receptors) influence
colonic motility. Mucosa-free longitudinal smooth muscle strips of the rat middle colon …

There is a degree of cervical relaxation in the ewe at estrus that is regulated by changes in
prostaglandin synthesis, prostaglandin receptor expression, and changes in the cervical …