Autophagy is a mechanism that enables cells to maintain cellular homeostasis by removing
damaged materials and mobilizing energy reserves in conditions of starvation. Although …

Objectives This study aims to summarise the evidence on more than 140 pharmacological
and non-pharmacological treatment options for major depressive disorder (MDD) and to …

Autism omics research has historically been reductionist and diagnosis centric, with little
attention paid to common co-occurring conditions (for example, sleep and feeding disorders) …

Major Depressive Disorder (MDD) is a highly prevalent psychiatric disorder worldwide. It
causes individual suffering, loss of productivity, increased health care costs and high suicide …

Introduction: Individuals suffering from psychiatric disorders experience high levels of illness
burden and a significantly reduced quality of life. Despite targeted psychopharmacological …

Cystathionine β‐synthase (CBS) regulates homocysteine metabolism and contributes to
hydrogen sulfide (H2S) biosynthesis through which it plays multifunctional roles in the …

Anxiety disorders are highly prevalent psychiatric disorders often comorbid with depression
and substance abuse. Twin studies have shown that anxiety disorders are moderately …

Objectives As clinical practice guidelines vary widely in their search strategies and
recommendations of complementary and alternative medicine (CAM) for depression, this …

Abstract S-Adenosyl methionine (SAMe), as a major methyl donor, exerts its influence on
central nervous system function through cellular transmethylation pathways, including the …

Depression is one of the most serious chronic psychiatric disorders affecting people
worldwide. Subthreshold depression (SD) is a form of subclinical depression with increased …