Osteoarthritis (OA) is the most common joint disease that causes pain and disability in the
adult population. OA is primarily caused by trauma induced by an external force or by age …

Improvements in health care and lifestyle have led to an elevated lifespan and increased
focus on age-associated diseases, such as neurodegeneration, cardiovascular disease …

Metabolic osteoarthritis (OA) has now been characterized as a subtype of OA, and links
have been discovered between this phenotype and metabolic syndrome (MetS)—both with …

Obesity, together with aging and injury, is among the main risk factors for osteoarthritis.
Obesity-related osteoarthritis can affect not only the weight-bearing joints, but also the …

Osteoarthritis (OA) is a heterogeneous disorder with several risk factors. Among them,
obesity has a major impact on both loading and non-loading joints. Mechanical overload …

Objective To investigate the effect of massive weight loss on (1) knee pain and disability,(2)
low-grade inflammation and metabolic status and (3) joint biomarkers in obese patients with …

Osteoarthritis (OA) is closely associated with aging, but its underlying mechanism is unclear.
Recent publications were reviewed to elucidate the connection between aging and OA. With …

Ammonia is a major pollutant in aquatic environments and poses a considerable threat to
the survival of fish. In this study, we investigated the toxic effects of ammonia on the …

Objective. To investigate whether advanced glycation end products (AGEs) induce the
expression of IL-6 and IL-8 through the receptor for AGEs (RAGE)-activated pathways in …

The accumulation of advanced oxidation protein products (AOPPs) has been linked to
vascular lesions in diabetes, chronic renal insufficiency, and atherosclerosis. However, the …