Structure-based multi-targeted molecular docking and molecular dynamic simulation analysis to identify potential inhibitors against ovarian cancer

BH Aloufi - Journal of Biochemical Technology, 2022 - jbiochemtech.com
Ovarian Cancer (OC) is among the most prevalent cancers in females. OC is one of the
deadliest and worst prognosis diseases. Currently, there are no approved OC screening …

Hypoglycemic activity and mechanisms of myricetin

J Qian, J Zhang, Y Chen, C Dai, J Fan… - Natural Product …, 2022 - Taylor & Francis
Myricetin has been reported to have a wide variety of beneficial physiological functions. The
present study was designed to investigate the mechanism of high purity myricetin, as a …

Protective effects of myricetin on benzo [a] pyrene-induced 8-hydroxy-2′-deoxyguanosine and BPDE-DNA adduct

SC Jee, M Kim, KS Kim, HS Kim, JS Sung - Antioxidants, 2020 - mdpi.com
Benzo [a] pyrene (B [a] P), a group 1 carcinogen, induces mutagenic DNA adducts. Myricetin
is present in many natural foods with diverse biological activities, such as anti-oxidative and …

Recent advances in natural polysaccharides against hepatocellular carcinoma: A review

D Wang, Z Zhang, L Zhao, L Yang, CJ Lou - International Journal of …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is a malignant tumor of the digestive system that poses a
serious threat to human life and health. Chemotherapeutic drugs commonly used in the …

Dietary phenolic acids and flavonoids as potential anti-cancer agents: current state of the art and future perspectives

RK Bonta - Anti-Cancer Agents in Medicinal Chemistry …, 2020 - ingentaconnect.com
Background: Cancer is a rapidly growing disease and the second most leading cause of
death worldwide. Breast, colon, lung, and prostate cancer are the most diagnosed types of …

Unveiling Neuroprotective Potential of Spice Plant‐Derived Compounds against Alzheimer's Disease: Insights from Computational Studies

MM Alom, RP Bonna, A Islam, MW Alom… - International Journal …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is a serious threat to the global health care system and is brought
on by a series of factors that cause neuronal dysfunction and impairment in memory and …

[HTML][HTML] Proximate composition, antioxidant, anti-inflammatory and anti-diabetic properties of the haustorium from Coconut (Cocos nucifera L.) and Palmyra palm …

A Narayanankutty, JT Job, AM Kuttithodi… - Journal of King Saud …, 2023 - Elsevier
Objective Functional foods play important roles in the management of health; the haustoria
from the Cocos nucifera and Borassus flabellifer are less explored for their nutritional …

Extraction and purification of total flavonoids from pine needles of Cedrus deodara contribute to anti-tumor in vitro

X Shi, D Liu, J Zhang, P Hu, W Shen, B Fan… - … and alternative medicine, 2016 - Springer
Background Cedrus deodara is one of the traditional Chinese medicinal herbs that exhibits
a line of biological activities. The current study extracted the total flavonoids from the pine …

Myricetin reverses epithelial–endothelial transition and inhibits vasculogenic mimicry and angiogenesis of hepatocellular carcinoma by directly targeting PAR1

M Wang, S Ren, Z Bi, L Zhang, M Cui… - Phytotherapy …, 2022 - Wiley Online Library
Most antiangiogenic inhibitors targeting endothelium‐dependent vessels cannot inhibit
tumor growth but promote tumor invasion and metastasis in some patients. Vasculogenic …

Molecular docking study of naturally derived flavonoids with antiapoptotic BCL-2 and BCL-XL proteins toward ovarian cancer treatment

MF Abd Ghani, R Othman, N Nordin - Journal of Pharmacy and …, 2020 - journals.lww.com
MATERIALS AND METHODS All the molecular docking functions in this study were
performed using AutoDock Vina.[11] This docking software has been reported to provide …