Spatially resolved molecular and cellular atlas of the mouse brain
L Han, Z Liu, Z Jing, Y Liu, H Chang, J Lei, Y Peng… - bioRxiv, 2023 - biorxiv.org
A comprehensive atlas of genes, cell types, and their spatial distribution across a whole
mammalian brain is fundamental for understanding function of the brain. Here, using snRNA …
mammalian brain is fundamental for understanding function of the brain. Here, using snRNA …
A robust and compact population code for competing sounds in auditory cortex
Cortical circuits encoding sensory information consist of populations of neurons, yet how
information aggregates via pooling individual cells remains poorly understood. Such pooling …
information aggregates via pooling individual cells remains poorly understood. Such pooling …
[HTML][HTML] Overexpression of the schizophrenia risk gene C4 in PV cells drives sex-dependent behavioral deficits and circuit dysfunction
SUMMARY Fast-spiking parvalbumin (PV)-positive cells are key players in orchestrating
pyramidal neuron activity, and their dysfunction is consistently observed in myriad brain …
pyramidal neuron activity, and their dysfunction is consistently observed in myriad brain …
Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex
R Francavilla, B Chattopadhyaya, JL Damo Kamda… - bioRxiv, 2024 - biorxiv.org
SYNGAP1 haploinsufficiency-related intellectual disability (SYNGAP1-ID) is characterized
by moderate to severe ID, generalized epilepsy, autism spectrum disorder, sensory …
by moderate to severe ID, generalized epilepsy, autism spectrum disorder, sensory …
Spike Reliability is Cell-Type Specific and Shapes Excitation and Inhibition in the Cortex
Neurons encode information in the highly variable spiking activity of neuronal populations,
so that different repetitions of the same stimulus can generate action potentials that vary …
so that different repetitions of the same stimulus can generate action potentials that vary …
Functional diversities within neurons and astrocytes in the adult rat auditory cortex revealed by single-nucleus RNA sequencing.
AG Aydin, A Lemenze, KM Bieszczad - bioRxiv, 2024 - biorxiv.org
The mammalian cerebral cortex is composed of a rich diversity of cell types. Cortical cells
are organized into networks that rely on their functional diversity to ultimately carry out a …
are organized into networks that rely on their functional diversity to ultimately carry out a …
Parvalbumin Neurons and Cortical Coding of Dynamic Stimuli: A Network Model
Cortical circuits feature both excitatory and inhibitory cells that underlie the encoding of
dynamic sensory stimuli, eg, speech, music, odors, and natural scenes. While previous …
dynamic sensory stimuli, eg, speech, music, odors, and natural scenes. While previous …