Recent advances in the field of nutrigenetics have provided evidence on how genetic
variations can impact the individuals' response to dietary intakes. An objective and reliable …

Abstract Background and Aims: The genetic risk score (GRS) is an important tool for
estimating the total genetic contribution or susceptibility to a certain outcome of interest in an …

Metabolic diseases have been shown to be associated with low vitamin D status; however,
the findings have been inconsistent. Hence, the objective of our study was to investigate the …

The Ghanaian population is experiencing an upsurge in obesity and type 2 diabetes (T2D)
due to rapid urbanization. Besides dietary factors, vitamin D-related genetic determinants …

Vitamin D deficiency is highly prevalent worldwide, and vitamin D-binding protein (DBP) a
major regulator of serum vitamin D levels. The rs4588 and rs7041 polymorphisms of the GC …

Background Some studies revealed that despite having sufficient sun exposure and dietary
supply, the level of serum 25 (OH) D in Bangladeshi adults is lower than its normal range …

This chapter describes the metabolic parameters of vitamin D and its metabolites according
to the framework of pharmacokinetics. The pharmacokinetics of vitamin D is considerably …

Background Genome-wide association studies in Western countries indicate a considerable
impact of variations in vitamin D binding protein (GC) genes on serum concentrations of 25 …

Given the relationship between vitamin D deficiency (VDD) and adverse outcomes of
metabolic diseases, we investigated the interplay of dietary and genetic components on …

Metabolic diseases have been shown to be associated with low vitamin D status; however,
the findings have been inconsistent. Hence, the objective of our study was to investigate the …