Dexmedetomidine: a review of its use for sedation in the intensive care setting

GM Keating - Drugs, 2015 - Springer
Dexmedetomidine (Dexdor®) is a highly selective α 2-adrenoceptor agonist. It has sedative,
analgesic and opioid-sparing effects and is suitable for short-and longer-term sedation in an …

Dexmedetomidine: a novel sedative-analgesic agent

R Gertler, HC Brown, DH Mitchell… - Baylor University …, 2001 - Taylor & Francis
Since the first report of clonidine, an α2-adrenoceptor agonist, the indications for this class of
drugs have continued to expand. In December 1999, dexmedetomidine was approved as …

右美托咪啶在临床麻醉中应用的研究进展

李民, 张利萍, 吴新民 - 中国临床药理学杂志, 2007 - cqvip.com
右美托咪啶为新型高选择性α2 肾上腺素能受体激动剂, 它具有剂量依赖性的镇静催眠作用,
还具有镇痛, 抑制交感活性, 无呼吸抑制等药理性质. 1999 年美国FDA 批准将其用于重症监护 …

右美托咪啶在麻醉中的应用

李天佐 - 北京医学, 2010 - cqvip.com
右美托咪啶在麻醉中的应用-[维普官方网站]-www.cqvip.com-维普网  我的维普 购物车 充值
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Dexmedetomidine

N Bhana, KL Goa, KJ McClellan - Drugs, 2000 - Springer
Abstract▴ Dexmedetomidine is a potent α 2-adrenoceptor agonist with 8 times higher affinity
for the α 2-adrenoceptorthan clonidine.▴ Dexmedetomidine has shown sedative, analgesic …

Dexmedetomidine: an updated review

AT Gerlach, JF Dasta - Annals of Pharmacotherapy, 2007 - journals.sagepub.com
Objective: To review recent literature on the safety and efficacy of dexmedetomidine. Data
Sources: Articles were identified through searches of MEDLINE (1966–January 2007). Key …

Comparison between dexmedetomidine and propofol for sedation in the intensive care unit: patient and clinician perceptions

RM Venn, RM Grounds - British journal of anaesthesia, 2001 - academic.oup.com
The α2 agonist dexmedetomidine is a new sedative and analgesic agent which is licensed
in the USA for post‐operative intensive care sedation. We compared dexmedetomidine with …

Dexmedetomidine: a review of its use for sedation in mechanically ventilated patients in an intensive care setting and for procedural sedation

SM Hoy, GM Keating - Drugs, 2011 - Springer
Dexmedetomidine (Precedex®), a pharmacologically active dextroisomer of medetomidine,
is a selective α 2-adrenergic receptor agonist. It is indicated in the US for the sedation of …

右美托咪定辅助全身麻醉患者的镇静及全身麻醉药物的节俭作用

高建瓴, 詹英, 杨建平, 金晓红, 李健 - 上海医学, 2010 - cqvip.com
目的评价右美托咪定用于全身麻醉患者的镇静效应及其对全身麻醉药物的节俭作用. 方法随机,
双盲, 安慰剂对照研究. 24 例年龄为18-65 岁的患者, 美国麻醉医师学会分级Ⅰ-Ⅱ 级 …

Dexmedetomidine: applications in pediatric critical care and pediatric anesthesiology

JD Tobias - Pediatric critical care medicine, 2007 - journals.lww.com
Objective: To provide a general descriptive account of the end-organ effects of
dexmedetomidine and to provide an evidence-based review of the literature regarding its …