Central respiratory chemoreception

PG Guyenet, RL Stornetta… - Journal of Comparative …, 2010 - Wiley Online Library
By definition central respiratory chemoreceptors (CRCs) are cells that are sensitive to
changes in brain PCO2 or pH and contribute to the stimulation of breathing elicited by …

Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults

JN Barnes, JL Taylor, BN Kluck… - Journal of applied …, 2013 - journals.physiology.org
Recently, several high-impact reviews suggest that regular aerobic exercise is beneficial for
maintaining cognitive function in aging adults. Higher cerebral blood flow and/or …

Human cerebrovascular and ventilatory CO2 reactivity to end‐tidal, arterial and internal jugular vein PCO2

K Peebles, L Celi, K McGrattan, C Murrell… - The Journal of …, 2007 - Wiley Online Library
This study examined cerebrovascular reactivity and ventilation during step changes in CO2
in humans. We hypothesized that:(1) end‐tidal P (P) would overestimate arterial P (P) during …

Ventilatory and cerebrovascular regulation and integration at high-altitude

RL Hoiland, CA Howe, GB Coombs… - Clinical Autonomic …, 2018 - Springer
Ascent to high-altitude elicits compensatory physiological adaptations in order to improve
oxygenation throughout the body. The brain is particularly vulnerable to the hypoxemia of …

Sex differences in the sympathetic neurocirculatory responses to chemoreflex activation

ALC Sayegh, JL Fan, LC Vianna… - The Journal of …, 2022 - Wiley Online Library
The purpose of this study was to determine whether there are sex differences in the
cardiorespiratory and sympathetic neurocirculatory responses to central, peripheral, and …

Rostral ventrolateral medulla and hypertension

PG Guyenet, RL Stornetta, BB Holloway… - …, 2018 - Am Heart Assoc
560 Hypertension September 2018 of interest in the potential contribution of sympatho-
respiratory coupling to SNA elevation in neurogenic hypertension. As summarized below …

Measuring the ventilatory response to hypoxia

J Duffin - The Journal of physiology, 2007 - Wiley Online Library
After defining the current approach to measuring the hypoxic ventilatory response this paper
explains why this method is not appropriate for comparisons between individuals or …

[HTML][HTML] Cerebral autoregulation is influenced by carbon dioxide levels in patients with septic shock

FS Taccone, D Castanares-Zapatero, D Peres-Bota… - Neurocritical care, 2010 - Springer
Background Altered brain perfusion may play an important role in the development of sepsis-
associated encephalopathy. However, whether or not cerebral autoregulation (CA) is …

Alterations in cerebral blood flow and cerebrovascular reactivity during 14 days at 5050 m

SJE Lucas, KR Burgess, KN Thomas… - The Journal of …, 2011 - Wiley Online Library
Non‐technical summary Brain blood flow increases during the first week of living at high
altitude. We do not understand completely what causes the increase or how the factors that …

Differential cerebrovascular CO2 reactivity in anterior and posterior cerebral circulations

RJ Skow, CM MacKay, MM Tymko, CK Willie… - Respiratory physiology …, 2013 - Elsevier
The potential differences in cerebrovascular responses between the anterior and posterior
circulations to changes in CO 2 are unclear in humans. Using transcranial Doppler …