Postnatal growth and development of the human body and its specific organs are regulated
by a complex network of local and systemic factors which is poorly understood. This review …

The somatotropic axis, consisting of growth hormone (GH), hepatic insulin‐like growth factor
I (IGF‐I), and assorted releasing factors, regulates growth and body composition …

IGF-I is a multipotent growth factor with important actions on normal tissue growth and
regeneration. In addition, IGF-I has been suggested to have beneficial effects on glucose …

Although the primary control of gonadotropin secretion is by the hypothalamic GnRH and the
gonadal function is controlled by the pituitary gonadotropins and prolactin, the emerging …

Background The hypothalamic‐pituitary‐gonadal (HPG) and hypothalamic‐pituitary‐
somatotropic (HPS) axes are strongly interconnected. Interactions between these axes are …

Acromegaly is a rare pathology characterized by chronic hypersecretion of Growth Hormone
(GH) and Insulin-like Growth Factor-1 (IGF-1) that causes somatic, metabolic, and systemic …

The action of growth hormone (GH) via its receptor involves many organ systems and
metabolic pathways. These diverse actions are reviewed in this paper in the context that …

The aim of the study was to investigate the longitudinal changes of inhibin B in a group of
patients with Klinefelter syndrome (KS; karyotype 47, XXY) progressing through puberty and …

Because insulin-like growth factor-I (IGF-I) is the best-characterized growth hormone (GH)-
dependent peptide, and because it has been measured extensively in a variety of clinical …

GH deficiency (GHD) in adult patients is a complex condition, mainly due to organic lesion of
hypothalamic-pituitary region and often associated with multiple pituitary hormone …