Emerging therapies and latest development in the treatment of unresectable pancreatic neuroendocrine tumors: an update for clinicians

J Sharma, M Duque, MW Saif - Therapeutic advances in …, 2013 - journals.sagepub.com
Pancreatic neuroendocrine tumors (pNETs) differ in their clinical behavior, presentation and
prognosis based on their initial histological features and disease stage. While small …

[HTML][HTML] Safety and efficacy of everolimus in Chinese patients with metastatic renal cell carcinoma resistant to vascular endothelial growth factor receptor-tyrosine …

J Guo, Y Huang, X Zhang, F Zhou, Y Sun, S Qin, Z Ye… - BMC cancer, 2013 - Springer
Abstract Background In China, there are currently no approved therapies for the treatment of
metastatic renal cell carcinoma (mRCC) following progression with vascular endothelial …

Drug-induced interstitial lung disease in molecular targeted therapies: high-resolution CT findings

F Sakai, T Johkoh, M Kusumoto, H Arakawa… - International journal of …, 2012 - Springer
Drug-induced lung injury (DLI) comprises a wide variety of pathologies, each with a unique
imaging pattern, so there are no characteristic imaging findings to establish diagnosis. When …

[HTML][HTML] Incidence and risk of treatment-related mortality in cancer patients treated with the mammalian target of rapamycin inhibitors

TK Choueiri, Y Je, G Sonpavde, CJ Richards… - Annals of oncology, 2013 - Elsevier
Background Inhibition of the mammalian target of rapamycin (mTOR) is an established
treatment for multiple malignancies. We carried out an up-to-date meta-analysis to …

Toxicity management of systemic kidney cancer therapies

Q Qin, E Nein, A Flaten… - Hematology/Oncology …, 2023 - hemonc.theclinics.com
Multiple systemic therapies are available for the treatment of metastatic renal cell carcinoma
(mRCC), including mammalian target of rapamycin (mTOR), vascular endothelial growth …

Bortezomib therapy‐related lung disease in J apanese patients with multiple myeloma: Incidence, mortality and clinical characterization

K Yoshizawa, HY Mukai, M Miyazawa, M Miyao… - Cancer …, 2014 - Wiley Online Library
Because of the potentially high mortality rate (6.5%) associated with bortezomib‐induced
lung disease (BILD) in J apanese patients with relapsed or refractory multiple myeloma, we …

[HTML][HTML] Biological therapies in breast cancer: common toxicities and management strategies

R Barroso-Sousa, IA Santana, L Testa… - The breast, 2013 - Elsevier
In recent years, a number of new molecules–commonly known as biological therapies–have
been approved or are in late stages of regulatory evaluation for the treatment of advanced …

Everolimus‐related pneumonitis in patients with metastatic breast cancer: incidence, radiographic patterns, and relevance to clinical outcome

C Gong, Q Xiao, Y Li, Y Gu, J Zhang, L Wang… - The …, 2021 - academic.oup.com
Background This study investigated the incidence, radiographic patterns, and relevance to
clinical outcome of everolimus‐related pneumonitis (ERP) in patients with metastatic breast …

Epidemiology and risk factors for severe delayed drug hypersensitivity reactions

ESR Gomes, ML Marques… - Current pharmaceutical …, 2019 - ingentaconnect.com
Severe delayed drug hypersensitivity reactions comprise different clinical entities and can
involve different immune-mediated mechanisms. Common examples are severe cutaneous …

[HTML][HTML] Everolimus in metastatic renal cell carcinoma patients intolerant to previous VEGFr-TKI therapy: a RECORD-1 subgroup analysis

S Bracarda, TE Hutson, C Porta, RA Figlin… - British journal of …, 2012 - nature.com
Background: A relevant percentage of patients with metastatic renal cell carcinoma develop
intolerance to vascular endothelial growth factor receptor-tyrosine kinase inhibitors (VEGFr …