Inflammatory Treg reprogramming in the tumor immune microenvironment
Regulatory T (Treg) cells, a subset of immune regulatory cells capable of triggering
immunological tolerance, are found within the intricate tumor immune microenvironment …
immunological tolerance, are found within the intricate tumor immune microenvironment …
Immunological Mechanisms behind Anti-PD-1/PD-L1 Immune Checkpoint Blockade: Intratumoral Reinvigoration or Systemic Induction?
Z Guo, J Yu, Z Chen, S Chen, L Wang - Biomedicines, 2024 - mdpi.com
Anti-PD-1/PD-L1 immune checkpoint blockade (ICB) has been widely used to treat many
types of cancer. It is well established that PD-L1 expressing cancer cells could directly inhibit …
types of cancer. It is well established that PD-L1 expressing cancer cells could directly inhibit …
Exosomes as drug delivery systems in glioma immunotherapy
X Hao, S Wang, L Wang, J Li, Y Li, J Liu - Journal of Nanobiotechnology, 2024 - Springer
Recently, the significant benefits of cancer immunotherapy for most cancers have been
demonstrated in clinical and preclinical studies. However, the efficacy of these …
demonstrated in clinical and preclinical studies. However, the efficacy of these …
Metformin-induced reduction of CCR8 enhances the anti-tumor immune response of PD-1 immunotherapy in glioblastoma
Y Li, B Liu, Y Cao, L Cai, Y Zhou, W Yang… - European Journal of …, 2024 - Elsevier
Immunotherapy strategies targeting the programmed cell death 1 (PD-1) in clinical
treatments have shown limited success in controlling glioblastoma malignancies. Metformin …
treatments have shown limited success in controlling glioblastoma malignancies. Metformin …
[HTML][HTML] Comprehensive assessment of regulatory T-cells-related scoring system for predicting the prognosis, immune microenvironment and therapeutic response in …
B Jiang, X Ye, W Wang, J He, S Zhang, S Zhang… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Abstract Introduction: Regulatory T cells (Tregs) play important roles in tumor
immunosuppression and immune escape. The aim of the present study was to construct a …
immunosuppression and immune escape. The aim of the present study was to construct a …
The Clinical Association Between the Inflammation-Nutritional Condition and Prognosis of Locally Advanced Intrahepatic Cholangiocarcinoma After R0 Resection …
G Huang, P Xi, Z Yao, C Zhao, X Li… - Journal of Inflammation …, 2024 - Taylor & Francis
Background Intrahepatic cholangiocarcinoma (ICC) correlates with poor outcomes,
necessitating the identification of prognostic factors from an inflammation-nutritional …
necessitating the identification of prognostic factors from an inflammation-nutritional …
[HTML][HTML] TNFSF9 Is Associated with Favorable Tumor Immune Microenvironment in Patients with Renal Cell Carcinoma Who Are Treated with the Combination …
B Isoda, S Kandori, T Sazuka, T Kojima… - … Journal of Molecular …, 2024 - ncbi.nlm.nih.gov
Combination therapy of nivolumab and ipilimumab (NIVO+ IPI) for metastatic renal cell
carcinoma (mRCC) has shown efficacy, but approximately 20% of patients experience …
carcinoma (mRCC) has shown efficacy, but approximately 20% of patients experience …
Single-Cell RNA Sequencing Revealed That the Enrichment of TPI1+ Malignant Hepatocytes Was Linked to HCC Metastasis and Immunosuppressive …
Y Liang, D Zhong, Q Yang, Y Tang, Y Qin… - Journal of …, 2024 - Taylor & Francis
Background Tumor metastasis is the leading cause of high mortality in hepatocellular
carcinoma (HCC). The metastasis-related HCC microenvironment is characterized by high …
carcinoma (HCC). The metastasis-related HCC microenvironment is characterized by high …
New insights into immune cells in cancer immunotherapy: from epigenetic modification, metabolic modulation to cell communication
S Qin, B Xie, Q Wang, R Yang, J Sun, C Hu, S Liu… - MedComm, 2024 - Wiley Online Library
Cancer is one of the leading causes of death worldwide, and more effective ways of
attacking cancer are being sought. Cancer immunotherapy is a new and effective …
attacking cancer are being sought. Cancer immunotherapy is a new and effective …
Multiple myeloma exosomal miRNAs suppress cGAS-STING antiviral immunity
X Chen, L Wang, Q Cheng, Z Deng, Y Tang… - … et Biophysica Acta (BBA …, 2024 - Elsevier
DNA virus infection is a significant cause of morbidity and mortality in patients with multiple
myeloma (MM). Monocyte dysfunction in MM patients plays a central role in infectious …
myeloma (MM). Monocyte dysfunction in MM patients plays a central role in infectious …