Significance: Optical imaging using the endogenous fluorescence of metabolic cofactors has
enabled nondestructive examination of dynamic changes in cell and tissue function both in …

Fluorescence lifetime imaging (FLIM) is a key fluorescence microscopy technique to map the
environment and interaction of fluorescent probes. It can report on photophysical events that …

Second‐harmonic generation (SHG) microscopy is a fantastic tool for imaging collagen and
probing its hierarchical organization from molecular scale up to tissue architectural level. In …

Visualization of biological processes and pathologic conditions at the cellular and tissue
levels largely relies on the use of fluorescence intensity signals from fluorophores or their …

The clinical applications of sensing tools (ie, biosensors) for the monitoring of
physiologically important analytes are very common. Nowadays, the biosensors are being …

Late state‐of‐the‐art analytical methodologies in chromatography, spectroscopy, and
electroanalysis have been developed to meet the challenges of changing environmental …

This review summarizes the historical and more recent developments of multiphoton
microscopy, as applied to dermatology. Multiphoton microscopy offers several advantages …

Multiphoton fluorescence lifetime imaging microscopy (MPM-FLIM) is extensively proposed
as a non-invasive optical method to study tissue metabolism. The approach is based on …

Neurotransmitters (NTs) are chemical messengers in the synaptic transmission process. NTs
play important roles in human activities, and imbalanced NTs levels in the body lead to …

Biomedical luminescence imaging in the near-infrared (NIR, 700-1700 nm) region has
shown great potential in visualizing biological processes and pathological conditions at …