Insulin resistance (IR) and cardiovascular disease (CVD) represent two universal public
health hazards, especially in today's Western societies. A causal-effect relationship has …

The liver acts as a manufacturing unit for the production of fetuin-A, which is essential for
various physiological characteristics. Scientific research has shown that a moderate upward …

Nonalcoholic fatty liver disease (NAFLD) is strongly associated to the features of metabolic
syndrome which can progress to cirrhosis, liver failure and hepatocellular carcinoma …

Urinary exosomes (UE) are small circular membranous vesicles with a lipid bilayer with a
diameter of 40–160 nm secreted by epithelial cells of the kidney and genitourinary system …

Fetuin-A, a plasma multifunctional protein known to play a role in insulin resistance, is
usually presented as a liver secreted protein. However, fetuin-A adipose tissue production …

Methods The PubMed, EMBASE, and Cochrane Library databases were searched to obtain
the potentially relevant studies up to May 2020. Standardized mean differences (SMD) and …

Purpose: Animal models show retinal ganglion cell (RGC) injuries that replicate features of
glaucoma and the contralateral eye is commonly used as an internal control. There is …

Fetuin-A, a hepatokine secreted by hepatocytes, binds to insulin receptors and consequently
impairs the activation of the insulin signaling pathway, leading to insulin resistance …

Cardiovascular disease and mineral bone disorders are major contributors to morbidity and
mortality among patients with chronic kidney disease and often persist after renal …

Patients with lean NAFLD make up an increasing subset of liver disease patients. The
association between lean NAFLD and feutin-A, which serves as a hepatokine and …