Growth factors, PI3K/AKT/mTOR and MAPK signaling pathways in colorectal cancer pathogenesis: where are we now?
C Stefani, D Miricescu, II Stanescu-Spinu… - International journal of …, 2021 - mdpi.com
Colorectal cancer (CRC) is a predominant malignancy worldwide, being the fourth most
common cause of mortality and morbidity. The CRC incidence in adolescents, young adults …
common cause of mortality and morbidity. The CRC incidence in adolescents, young adults …
[HTML][HTML] Review on circular RNAs and new insights into their roles in cancer
X Tang, H Ren, M Guo, J Qian, Y Yang, C Gu - … and structural biotechnology …, 2021 - Elsevier
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …
EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3
Z Pan, R Zhao, B Li, Y Qi, W Qiu, Q Guo, S Zhang… - Molecular cancer, 2022 - Springer
Background Gliomas are the most common malignant primary brain tumours with a highly
immunosuppressive tumour microenvironment (TME) and poor prognosis. Circular RNAs …
immunosuppressive tumour microenvironment (TME) and poor prognosis. Circular RNAs …
Lnc2Cancer 3.0: an updated resource for experimentally supported lncRNA/circRNA cancer associations and web tools based on RNA-seq and scRNA-seq data
Y Gao, S Shang, S Guo, X Li, H Zhou, H Liu… - Nucleic acids …, 2021 - academic.oup.com
Abstract An updated Lnc2Cancer 3.0 (http://www. bio-bigdata. net/lnc2cancer or http://bio-
bigdata. hrbmu. edu. cn/lnc2cancer) database, which includes comprehensive data on …
bigdata. hrbmu. edu. cn/lnc2cancer) database, which includes comprehensive data on …
The circular RNA circHMGB2 drives immunosuppression and anti-PD-1 resistance in lung adenocarcinomas and squamous cell carcinomas via the miR-181a-5p …
LX Zhang, J Gao, X Long, PF Zhang, X Yang, SQ Zhu… - Molecular Cancer, 2022 - Springer
Background Previous studies have confirmed the oncogenic role of HMGB2 in various
cancers, but the biological functions of HMGB2-derived circRNAs remain unknown. Thus …
cancers, but the biological functions of HMGB2-derived circRNAs remain unknown. Thus …
Mutual regulation between N6-methyladenosine (m6A) modification and circular RNAs in cancer: impacts on therapeutic resistance
H Lin, Y Wang, P Wang, F Long, T Wang - Molecular cancer, 2022 - Springer
The resistance of tumor cells to therapy severely impairs the efficacy of treatment, leading to
recurrence and metastasis of various cancers. Clarifying the underlying mechanisms of …
recurrence and metastasis of various cancers. Clarifying the underlying mechanisms of …
Single-cell sequencing: a promising approach for uncovering the mechanisms of tumor metastasis
Y Han, D Wang, L Peng, T Huang, X He… - Journal of hematology & …, 2022 - Springer
Single-cell sequencing (SCS) is an emerging high-throughput technology that can be used
to study the genomics, transcriptomics, and epigenetics at a single cell level. SCS is widely …
to study the genomics, transcriptomics, and epigenetics at a single cell level. SCS is widely …
circRNA-miRNA-mRNA regulatory network in human lung cancer: an update
ZZ Liang, C Guo, MM Zou, P Meng, TT Zhang - Cancer cell international, 2020 - Springer
Circular RNAs, as hopeful diagnosis markers and therapeutic molecules, have been
studied, probed and applied into several diseases, such as cardiovascular diseases …
studied, probed and applied into several diseases, such as cardiovascular diseases …
[HTML][HTML] CircITGB6 promotes ovarian cancer cisplatin resistance by resetting tumor-associated macrophage polarization toward the M2 phenotype
H Li, F Luo, X Jiang, W Zhang, T Xiang… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background Platinum resistance is a major challenge in the clinical treatment of advanced
ovarian cancer (OC). Accumulating evidence shows that the tumor-promotive M2 …
ovarian cancer (OC). Accumulating evidence shows that the tumor-promotive M2 …
Functions and mechanisms of circular RNAs in cancer radiotherapy and chemotherapy resistance
C Cui, J Yang, X Li, D Liu, L Fu, X Wang - Molecular cancer, 2020 - Springer
Circular RNAs (circRNAs), one type of non-coding RNA, were initially misinterpreted as
nonfunctional products of pre-mRNA mis-splicing. Currently, circRNAs have been proven to …
nonfunctional products of pre-mRNA mis-splicing. Currently, circRNAs have been proven to …